SCHEMBL4352284

SCHEMBL4352284

CC1C=CC[C@H]2C(=O)OC(=O)[C@@H]12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.41
MEN1 O00255 3/20 0.41
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
PPM1B O75688 1/20 0.33
PPP1CC P36873 1/20 0.33
TFPI2 P48307 1/20 0.33
RAB9A P51151 1/20 0.33
PPP5C P53041 1/20 0.33
PPP1CA P62136 1/20 0.33
PMP22 Q01453 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
CYP2D6 P10635 1/20 0.33
NFKB1 P19838 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1739727 1.00 KMT2A (0.41) KMT2AMEN1LMNASMN1; SMN2HTT
SCHEMBL7175398 1.00 KMT2A (0.41) KMT2AMEN1LMNASMN1; SMN2HTT
SCHEMBL11766943 1.00 KMT2A (0.41) KMT2AMEN1LMNASMN1; SMN2HTT
SCHEMBL1473414 1.00 KMT2A (0.41) KMT2AMEN1LMNASMN1; SMN2HTT
SCHEMBL13719383 0.78 KDM4E (0.31) KMT2AMEN1LMNASMN1; SMN2KDM4E
SCHEMBL6705482 0.78 KDM4E (0.31) LMNASMN1; SMN2L3MBTL1KDM4EGMNN
SCHEMBL10592596 0.77 KDM4E (0.33) LMNASMN1; SMN2KDM4EGMNNPPM1B
SCHEMBL19604088 0.77 KDM4E (0.33) LMNASMN1; SMN2KDM4EGMNNPPM1B
SCHEMBL1071613 0.77 KDM4E (0.33) LMNASMN1; SMN2KDM4EGMNNPPM1B
SCHEMBL9619474 0.77 FNTA (0.31) LMNASMN1; SMN2KDM4EGMNNPPM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed
EP-0340019-A2 Resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-11-02 EP disclosed