Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 9/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436724 | 0.98 | OPRL1 (0.58) | OPRL1PTGDR2HTR2AHTR2CHTR2B | |
| SCHEMBL435077 | 0.94 | OPRL1 (0.54) | OPRL1PTGDR2HTR2AHTR2CHTR2B | |
| SCHEMBL434354 | 0.89 | OPRL1 (0.57) | OPRL1HTR2AHTR2CHTR2BCHRNB2 | |
| SCHEMBL29266754 | 0.86 | OPRL1 (0.56) | OPRL1HTR2AHTR2CHTR2BTP53 | |
| SCHEMBL28095108 | 0.81 | GAA (0.45) | OPRL1PTGDR2NPC1RAB9A | |
| SCHEMBL11773147 | 0.81 | KDM1A (0.52) | OPRL1PTGDR2NPC1CHRNB2CHRNB4 | |
| SCHEMBL24736536 | 0.80 | OPRL1 (0.48) | OPRL1PTGDR2HTR2AHTR2CHTR2B | |
| SCHEMBL8785375 | 0.80 | PTGDR2 (0.44) | OPRL1PTGDR2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5019341 | 0.80 | OPRL1 (0.50) | OPRL1HTR2AHTR2CHTR2BCHRNB2 | |
| SCHEMBL5100126 | 0.80 | KDM1A (0.53) | OPRL1PTGDR2NPC1RAB9APTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |