Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414275 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL29352295 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL29414264 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL192419 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL31265362 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL27816522 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL30332559 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL608537 | 0.96 | ALDH1A1 (0.58) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL29355309 | 0.93 | ALDH1A1 (0.55) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 | |
| SCHEMBL21447 | 0.93 | ALDH1A1 (0.61) | ALDH1A1HSD17B10MAPK1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | claimed |
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054649-A1 | Bridged Organosilane and Production Method Thereof | C5, CCNE1, QSOX1 | ALDH1A1 866/4885HSD17B10 4059/4885MAPK1 3078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.