SCHEMBL4352639

SCHEMBL4352639

Fc1ccc(-c2ccc(F)c(Br)c2)cc1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.42
VCP P55072 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2B Q13224 1/20 0.39
APEX1 P27695 1/20 0.38
KDM4E B2RXH2 1/20 0.37
KIF11 P52732 1/20 0.37
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP11B1 P15538 3/20 0.33
CYP11B2 P19099 3/20 0.33
MAPK14 Q16539 1/20 0.33
CYP17A1 P05093 1/20 0.33
ABCC9 O60706 2/20 0.33
ABCC8 Q09428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfur Dioxide SCHEMBL23270393 0.90 PARP1 (0.41) PARP1VCPGRIN1GRIN2BAPEX1
SCHEMBL18782552 0.90 MAOB (0.39) PARP1VCPGRIN1GRIN2BHSD17B1
SCHEMBL456798 0.88 CRHBP (0.50) KDM4EKIF11HSD17B1HSD17B2CYP1A2
SCHEMBL30318876 0.88 CRHBP (0.50) KDM4EKIF11HSD17B1HSD17B2CYP1A2
SCHEMBL31348999 0.86 ESR2 (0.50) KIF11HSD17B1HSD17B2
SCHEMBL8383368 0.86 TAAR1 (0.50) PARP1VCPGRIN1GRIN2BKDM4E
SCHEMBL31528276 0.82 PARP1 (0.35) PARP1VCPGRIN1GRIN2BKDM4E
SCHEMBL15234719 0.81 KIF11 (0.54) KIF11CYP11B1CYP11B2
SCHEMBL8203055 0.78 DYRK1A (0.50) CYP2D6CYP11B2MAPK14
SCHEMBL27688213 0.78 PARP1 (0.33) PARP1VCPGRIN1GRIN2BHSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8288058-B2 Binder for fuel cell, composition for forming electrode, electrode, and fuel cell using the electrode MITSUI CHEMICALS, INC. (JP) 2012-10-16 US disclosed
EP-1788649-B1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE MITSUI CHEMICALS INC (JP) 2012-09-26 EP disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20070292733-A1 Binder for Fuel Cell, Composition for Forming Electrode, Electrode, and Fuel Cell Using the Electrode MITSUI CHEMICALS, INC. (JP) 2007-12-20 US disclosed
EP-1788649-A1 BINDER FOR FUEL CELL, COMPOSITION FOR ELECTRODE FORMATION, ELECTRODE, AND FUEL CELL USING THE ELECTRODE Mitsui Chemicals, Inc. (JP) 2007-05-23 EP disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed