Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20563993 | 0.95 | TSHR (0.32) | TSHRPOLBMAPK1HSD17B10 | |
| SCHEMBL3195517 | 0.95 | TSHR (0.34) | TSHRPOLBMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL10054316 | 0.95 | TSHR (0.34) | TSHRPOLBMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL20563991 | 0.93 | TSHR (0.33) | TSHRPOLBMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL19101406 | 0.87 | MEN1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL1131935 | 0.87 | MEN1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL12652017 | 0.85 | — | — | |
| SCHEMBL4352824 | 0.84 | TSHR (0.37) | TSHRPOLBMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL3183822 | 0.84 | TSHR (0.34) | TSHRPOLBMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL15803995 | 0.81 | TSHR (0.33) | TSHRPOLBMAPK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021104547-A1 | COMPOUNDS FOR MODIFICATION OF NEGATIVELY CHARGED CARRIER SURFACE, METHOD OF THEIR PREPARATION AND USE THEREOF | UNIVERZITA KARLOVA (CZ) | 2021-06-03 | — | — | WO | disclosed |
| CN-109929003-A | The tetraphenyl ethylene compound of the glycosyl units containing sialic acid, preparation method and application | 北京师范大学 | 2019-06-25 | — | — | CN | disclosed |
| US-9777034-B2 | Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-10-03 | — | — | US | disclosed |
| US-9427483-B2 | Radioisotope trithiol complexes | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2016-08-30 | — | — | US | disclosed |
| US-20160108076-A1 | MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES | NATIONAL SCIENCE FOUNDATION | 2016-04-21 | — | — | US | disclosed |
| US-20150283274-A1 | RADIOISOTOPE TRITHIOL COMPLEXES | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2015-10-08 | — | — | US | disclosed |
| WO-2009110971-A2 | PROCESS FOR CONVERTING MULTIFUNCTIONAL ALIPHATIC ALCOHOLS | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009110971-A2 | PROCESS FOR CONVERTING MULTIFUNCTIONAL ALIPHATIC ALCOHOLS | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150283274-A1 | RADIOISOTOPE TRITHIOL COMPLEXES | ICMT, QTRT1, QPCT | TSHR 38/4885POLB 1577/4885MAPK1 4096/4885 |
| US-20160108076-A1 | MODULAR SYNTHESIS OF AMPHIPHILIC JANUS GLYCODENDRIMERS AND THEIR SELF-ASSEMBLY INTO GLYCODENDRIMERSOMES | C1S, PYM1, DEGS1 | TSHR 1820/4885POLB 4262/4885MAPK1 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.