SCHEMBL4352840

SCHEMBL4352840

CCC(=O)OCC(O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 5/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
ALDH1A1 P00352 2/20 0.43
KDM4E B2RXH2 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
PKM P14618 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
KMT2A Q03164 1/20 0.43
BCAT2 O15382 1/20 0.42
MMP8 P22894 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
POLB P06746 1/20 0.41
ASAH1 Q13510 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28604790 0.86 LMNA (0.48) LMNASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL19275401 0.85 CA12 (0.50) LMNASMN1; SMN2ALDH1A1KDM4ECYP1A2
SCHEMBL10495922 0.84 TDP1 (0.44) LMNASMN1; SMN2ALDH1A1KDM4ECYP1A2
SCHEMBL27751396 0.83 CYP19A1 (0.39) LMNASMN1; SMN2ALDH1A1KDM4ECYP1A2
SCHEMBL27751397 0.83 CYP19A1 (0.39) LMNASMN1; SMN2ALDH1A1KDM4ECYP1A2
SCHEMBL6909304 0.82 ASAH1 (0.56) LMNASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL27686619 0.82 CYP1A2 (0.43) LMNASMN1; SMN2ALDH1A1CYP1A2CYP2D6
SCHEMBL10909299 0.82 SMN1; SMN2 (0.43) LMNASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL10362252 0.81 ALDH1A1 (0.50) LMNASMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL5566856 0.81 ALDH1A1 (0.50) LMNASMN1; SMN2NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0102193-B1 STABILIZERS FOR SYNTHETIC RESINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-29 EP claimed
CN-106061943-B It can be used as the bicyclic pyrrole derivatives of the agonist of GPR120 詹森药业有限公司 2019-11-05 CN disclosed
CN-110172136-A A kind of composition epoxy resin of resisting high-temperature yellowing and preparation method thereof 深圳市安品有机硅材料有限公司 2019-08-27 CN disclosed
CN-107304379-B A kind of combustion gas turbine oil composition and preparation method thereof 中国石油化工股份有限公司 2019-08-16 CN disclosed
CN-105979942-B For treatment or lenitive sulfamate derivatives 比皮艾思药物研发有限公司 2018-12-07 CN disclosed
CN-107922432-A Novel hydroxy acid derivatives, process for their preparation and pharmaceutical compositions containing them 法国施维雅药厂 2018-04-17 CN disclosed
CN-107663426-A Double-sided adhesive sheet 日东电工株式会社 2018-02-06 CN disclosed
CN-107629711-A Optical double-sided adhesive tape 日东电工株式会社 2018-01-26 CN disclosed
CN-107629710-A Surface protective film 日东电工株式会社 2018-01-26 CN disclosed
CN-107541149-A Optical-use pressure-sensitive adhesive sheet, polarizing coating and liquid crystal display device with adhesive phase 日东电工株式会社 2018-01-05 CN disclosed
CN-105209444-B It can be used as the benzo-fused heterocycle derivative of GPR120 activator 詹森药业有限公司 2017-12-29 CN disclosed
CN-107304382-A A kind of air compressor oil composition and preparation method thereof 中国石油化工股份有限公司 2017-10-31 CN disclosed
CN-107163867-A Optical-use pressure-sensitive adhesive sheet, polarizing coating and liquid crystal display device with adhesive phase 日东电工株式会社 2017-09-15 CN disclosed
CN-106061943-A Bicyclic pyrrole derivatives useful as agonists of GPR120 詹森药业有限公司 2016-10-26 CN disclosed
CN-105979942-A Sulfamate derivative compounds for use in treating or alleviating pain 比皮艾思药物研发有限公司 2016-09-28 CN disclosed
CN-104855416-A High-temperature-resistant composite antibacterial agent and preparation method thereof WUHAN JASON BIOTECH CO LTD 2015-08-26 CN disclosed
US-20090312478-A1 VINYL CHLORIDE RESIN COMPOSITION ADEKA CORPORATION (JP) 2009-12-17 US disclosed