SCHEMBL4353023

SCHEMBL4353023

O=C(O)C1(C(=O)O)CCC(Cl)CC1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 3/20 0.37
GRM3 Q14832 3/20 0.37
CYP2C19 P33261 3/20 0.37
GRM4 Q14833 2/20 0.37
CYP1A2 P05177 2/20 0.37
ALOX15 P16050 2/20 0.37
LMNA P02545 2/20 0.37
MTOR P42345 2/20 0.37
GRM8 O00222 2/20 0.37
GRM6 O15303 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
GRM5 P41594 1/20 0.37
GRM1 Q13255 1/20 0.37
PLCB1 Q9NQ66 1/20 0.37
TSHR P16473 1/20 0.37
FFAR3 O14843 1/20 0.33
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 2/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7036505 0.81 GRM2 (0.50) GRM2GRM3CYP2C19GRM4CYP1A2
SCHEMBL4650803 0.80 CYP2D6 (0.35) GRM2GRM3CYP2C19GRM4CYP1A2
SCHEMBL5014634 0.78 TSHR (0.33) GRM2GRM3CYP2C19GRM4CYP1A2
SCHEMBL11820173 0.76 CYP2C19 (0.35) GRM2GRM3CYP2C19GRM4CYP1A2
SCHEMBL3420703 0.76 CYP2C19 (0.38) GRM2GRM3CYP2C19GRM4CYP1A2
SCHEMBL9397974 0.76 GRM2 (0.35) GRM2GRM3CYP2C19GRM4CYP1A2
SCHEMBL10711599 0.75 GRM2 (0.32) GRM2GRM3CYP2C19GRM4CYP1A2
SCHEMBL8641820 0.75 FFAR3 (0.44) CYP2C19FFAR3CYP2D6
SCHEMBL106415 0.75
SCHEMBL23458958 0.74 FFAR3 (0.62) GRM2GRM3CYP2C19GRM4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102574992-B Liquid crystalline polymer and molded article POLYPLASTICS CO 2015-03-11 CN disclosed
EP-1382437-B1 Thermal conductive polymer molded article and method for producing the same POLYMATECH CO LTD (JP) 2012-09-12 EP disclosed
US-7540991-B2 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. (JP) 2009-06-02 US disclosed
US-7347955-B2 Thermoconductive molecular oriented liquid crystal polymers used as heat exchanger in electronics POLYMATECH CO., LTD. (JP) 2008-03-25 US disclosed
EP-1615286-B1 Ion conductive polymer electrolyte membrane and production method for the same POLYMATECH CO LTD (JP) 2007-09-12 EP disclosed
US-7189778-B2 Thermally conductive polymer molded article and method for producing the same POLYMATECH CO., LTD. (JP) 2007-03-13 US disclosed
US-7079405-B2 Thermal conductive polymer molded article and method for producing the same POLYMATECH CO., LTD. (JP) 2006-07-18 US disclosed
EP-1416031-B1 Heat conducting polymer mold products POLYMATECH CO LTD (JP) 2006-05-24 EP disclosed
EP-1615286-A1 Ion conductive polymer electrolyte membrane and production method for the same Polymatech Co., Ltd. (JP) 2006-01-11 EP disclosed
US-20060004112-A1 Molecular chains of the liquid crystalline polymer (e.g. polybenzoxazole, polybenzothiazole, and polybenzimidazole) having an ionic disosciative group and molecular chain orientated in a specific direction; allows permeation of hydrogen ions generated at a fuel electrode (anode) to cathode POLYMATECH CO., LTD. 2006-01-05 US disclosed
EP-0264290-A2 Composition for injection moulding POLYPLASTICS CO. LTD. (JP) 1988-04-20 EP disclosed
US-4726998-A LIQUID CRYSTAL POLYMER SUBSTRATE, MAGNETIC LAYER POLYPLASTICS CO., LTD. (JP) 1988-02-23 US disclosed
US-4710547-A IMMOBILIZATION CELANESE CORPORATION (US) 1987-12-01 US disclosed
EP-0231606-A2 Polyester composition POLYPLASTICS CO. LTD. (JP) 1987-08-12 EP disclosed
EP-0226361-A1 Electrically conductive resin composition POLYPLASTICS CO. LTD. (JP) 1987-06-24 EP disclosed
EP-0214827-A2 Surface-metallized, moulded resin article POLYPLASTICS CO. LTD. (JP) 1987-03-18 EP disclosed
EP-0206599-A2 Magnetic disk POLYPLASTICS CO. LTD. (JP) 1986-12-30 EP disclosed
EP-0206600-A2 Method for molding a gear wheel POLYPLASTICS CO. LTD. (JP) 1986-12-30 EP disclosed
US-4626371-A ANISOTROPIC POLYMERS CELANESE CORPORATION (US) 1986-12-02 US disclosed
EP-0184367-A1 Process for producing electroconductive resin composite POLYPLASTICS CO. LTD. (JP) 1986-06-11 EP disclosed