Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | GRM8 | O00222 | 2/20 | 0.32 |
| ▸ | GRM6 | O15303 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650803 | 0.80 | CYP2D6 (0.35) | TSHRFFAR3GRM2GRM3GRM4 | |
| SCHEMBL27788454 | 0.79 | GRM4 (0.35) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL4353023 | 0.78 | GRM2 (0.37) | TSHRFFAR3GRM2GRM3GRM4 | |
| SCHEMBL3420703 | 0.76 | CYP2C19 (0.38) | TSHRFFAR3GRM2GRM3GRM4 | |
| SCHEMBL7036505 | 0.76 | GRM2 (0.50) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL9397974 | 0.76 | GRM2 (0.35) | TSHRGRM2GRM3GRM4CYP2C19 | |
| SCHEMBL4264213 | 0.76 | EPHX2 (0.32) | TSHRFFAR3EPHX2GRM2GRM3 | |
| SCHEMBL3819279 | 0.76 | EPHX2 (0.32) | TSHRFFAR3EPHX2GRM2GRM3 | |
| SCHEMBL106415 | 0.75 | — | — | |
| SCHEMBL8641820 | 0.75 | FFAR3 (0.44) | FFAR3CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015035446-A1 | MACROMOLECULES OF DENDRIMER-PLATINUM CONJUGATES | STARPHARMA PTY LTD (AU) | 2015-03-19 | — | — | WO | disclosed |
| EP-1967520-A2 | Production of polyketides and other natural products | Biotica Technology Limited (GB) | 2008-09-10 | — | — | EP | disclosed |