Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.67 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 5/20 | 0.55 |
| ▸ | PPARD | Q03181 | 5/20 | 0.55 |
| ▸ | PPARA | Q07869 | 5/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5311340 | 1.00 | LMNA (0.79) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL10764903 | 1.00 | LMNA (0.79) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Cyclohexane SCHEMBL28096964 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| SCHEMBL27965235 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2538446 | 0.97 | LMNA (0.73) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL8997800 | 0.97 | LMNA (0.73) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL258769 | 0.97 | LMNA (0.73) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2791026 | 0.97 | LMNA (0.73) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL27756876 | 0.97 | LMNA (0.73) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Cyclohexane SCHEMBL28181958 | 0.97 | TSHR (0.80) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090169772-A1 | RETARDATION FILM, METHOD FOR PRODUCING RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY | KONICA MINOLTA OPTO, INC. (JP) | 2009-07-02 | — | — | US | disclosed |