Adipic Acid

Adipic Acid

SCHEMBL8997800

C1CCCC1.N.N.O=C(O)CCCCC(=O)O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC18A2SLC6A2SLC6A3

The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.73
TSHR P16473 4/20 0.69
NFKB1 P19838 2/20 0.69
PMP22 Q01453 1/20 0.69
SLC22A6 Q4U2R8 2/20 0.62
GPR84 Q9NQS5 4/20 0.55
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 2/20 0.55
AKR1B1 P15121 1/20 0.55
CYP2D6 P10635 1/20 0.55
FOLH1 Q04609 1/20 0.55
CYP1A2 P05177 1/20 0.54
MAPK1 P28482 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
CAMK2A Q9UQM7 1/20 0.53
PPARG P37231 5/20 0.52
PPARD Q03181 5/20 0.52
PPARA Q07869 5/20 0.52
HDAC11 Q96DB2 4/20 0.52
ALDH1A1 P00352 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL2791026 1.00 LMNA (0.73) LMNATSHRNFKB1PMP22SLC22A6
Adipic Acid SCHEMBL258769 1.00 LMNA (0.73) LMNATSHRNFKB1PMP22SLC22A6
Adipic Acid SCHEMBL2538446 1.00 LMNA (0.73) LMNATSHRNFKB1PMP22SLC22A6
Azelaic Acid SCHEMBL6371638 0.97 TSHR (0.75) LMNATSHRNFKB1PMP22SLC22A6
Sebacic Acid SCHEMBL631755 0.97 TSHR (0.75) LMNATSHRNFKB1PMP22SLC22A6
Cyclohexane SCHEMBL10454181 0.97 TSHR (0.75) LMNATSHRNFKB1PMP22SLC22A6
Sebacic Acid SCHEMBL11658052 0.97 TSHR (0.75) LMNATSHRNFKB1PMP22SLC22A6
Adipic Acid SCHEMBL4353087 0.97 LMNA (0.79) LMNATSHRNFKB1PMP22SLC22A6
Adipic Acid SCHEMBL5311340 0.97 LMNA (0.79) LMNATSHRNFKB1PMP22SLC22A6
Adipic Acid SCHEMBL10764903 0.97 LMNA (0.79) LMNATSHRNFKB1PMP22SLC22A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034239-B2 Method of fabricating a fiber ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2015-05-19 US claimed
US-20130149532-A1 FIBER FABRICATION METHOD AND THE FIBER FABRICATED THEREBY ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2013-06-13 US claimed
CN-107353198-B Pentanediamine adipate and crystal thereof 南京工业大学 2020-11-06 CN disclosed
US-9034239-B2 Method of fabricating a fiber ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2015-05-19 US disclosed
US-20130149532-A1 FIBER FABRICATION METHOD AND THE FIBER FABRICATED THEREBY ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2013-06-13 US disclosed
EP-0590054-B1 COPOLYADIPAMIDE CONTAINING PENTAMETHYLENEADIPAMIDE UNITS AND PRODUCTS PREPARED THEREFROM DU PONT (US) 1996-09-04 EP disclosed
EP-0590054-A1 COPOLYADIPAMIDE CONTAINING PENTAMETHYLENEADIPAMIDE UNITS AND PRODUCTS PREPARED THEREFROM. DU PONT (US) 1994-04-06 EP disclosed
US-5185428-A Relative viscosity greater than about twenty-five E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-02-09 US disclosed
WO-1993000385-A1 COPOLYADIPAMIDE CONTAINING PENTAMETHYLENEADIPAMIDE UNITS AND PRODUCTS PREPARED THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-07 WO disclosed