SCHEMBL43536

SCHEMBL43536

COc1cc(C(O)CO)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 1.00
CYP3A4 P08684 2/20 1.00
NFKB1 P19838 2/20 0.73
BLM P54132 2/20 0.71
PMP22 Q01453 1/20 0.71
SLC22A3 O75751 1/20 0.65
NPSR1 Q6W5P4 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.56
MMP1 P03956 1/20 0.54
BCHE P06276 2/20 0.53
TYR P14679 2/20 0.53
ACHE P22303 2/20 0.53
PPARG P37231 1/20 0.51
PPARD Q03181 1/20 0.51
PPARA Q07869 1/20 0.51
STAT3 P40763 1/20 0.50
MAOB P27338 1/20 0.50
GAA P10253 1/20 0.49
FOS P01100 1/20 0.49
TTR P02766 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31254086 1.00 TSHR (1.00) TSHRCYP3A4NFKB1BLMPMP22
SCHEMBL29776919 1.00 TSHR (1.00) TSHRCYP3A4NFKB1BLMPMP22
SCHEMBL31254076 1.00 TSHR (1.00) TSHRCYP3A4NFKB1BLMPMP22
SCHEMBL31364250 1.00 TSHR (1.00) TSHRCYP3A4NFKB1BLMPMP22
Sulfuric Acid SCHEMBL31254117 0.92 TSHR (0.85) TSHRCYP3A4NFKB1BLMPMP22
Sulfuric Acid SCHEMBL31006937 0.92 TSHR (0.85) TSHRCYP3A4NFKB1BLMPMP22
Sulfuric Acid SCHEMBL11041301 0.92 TSHR (0.85) TSHRCYP3A4NFKB1BLMPMP22
Piperazine SCHEMBL31187001 0.91 CYP3A4 (0.82) TSHRCYP3A4NFKB1BLMPMP22
SCHEMBL8082807 0.87 TSHR (0.77) TSHRCYP3A4NFKB1BLMPMP22
SCHEMBL29761292 0.87 TSHR (0.77) TSHRCYP3A4NFKB1BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 746 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260002951-A1 METHOD FOR PROVIDING INFORMATION FOR BRAIN DOPING DIAGNOSIS KOREA INST SCI & TECH (KR) 2026-01-01 US claimed
US-20250304940-A1 PROGRAMMABLE ADENINE BASE EDITOR AND USES THEREOF HUIDAGENE THERAPEUTICS (SINGAPORE) PTE. LTD. (SG) 2025-10-02 US claimed
CN-119985745-A Detection method for micromolecular phenolic substances and application thereof 北京中医药大学 2025-05-13 CN claimed
EP-4522738-A1 PROGRAMMABLE ADENINE BASE EDITOR AND USES THEREOF Huidagene Therapeutics (Singapore) Pte. Ltd. (SG) 2025-03-19 EP claimed
CN-119630788-A Programmable adenine base editor and use thereof 辉大(上海)生物科技有限公司 2025-03-14 CN claimed
US-20250009655-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC 2025-01-09 US claimed
CN-119104708-A Application of kynurenine, formyl-5-hydroxykynurenine and 3-methoxy-4-hydroxyphenylethylene glycol as serum biomarker for evaluating curative effect of Crohn disease 济南微生态生物医学省实验室 2024-12-10 CN claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
CN-118688315-A Multichannel high-coverage synchronous quantification method for amino-containing and hydroxyl-containing compounds 复旦大学 2024-09-24 CN claimed
CN-116445463-B Novel plant base editor pAYBEs 中国农业科学院作物科学研究所 2024-06-14 CN claimed
WO-2007119004-A2 METHOD FOR DIAGNOSING IN VITRO OR EX VIVO PSYCHIATRIC DISORDERS AND/OR INTESTINAL DYSBIOSES AURE (FR) 2007-10-25 WO claimed
EP-1328261-A2 TREATMENT OF NEURODEGENERATIVE DISEASE Minerva Biotechnologies Corporation (US) 2003-07-23 EP claimed
US-20030060487-A1 Treatment of neurodegenerative disease MINERVA BIOTECHNOLOGIES CORPORATION 2003-03-27 US claimed
WO-2001078709-A2 TREATMENT OF NEURODEGENERATIVE DISEASE MINERVA BIOTECHNOLOGIES CORPORATION (US) 2001-10-25 WO claimed
EP-0746986-B1 Delayed release flavourant compositions GIVAUDAN ROURE INT (CH) 2000-08-23 EP claimed
US-5227472-A Antigen for producing an antibody against MHPG DAIICHI RADIOISOTOPE LABORATORIES, LTD. (JP) 1993-07-13 US claimed
US-5145791-A Immunology ABBOTT LABORATORIES (US) 1992-09-08 US claimed
EP-0252405-A2 3-methoxy-4-hydroxyphenylglycol fluorescence polarization immunoassay ABBOTT LABORATORIES (US) 1988-01-13 EP claimed
US-4311790-A SOLVENT EXTRACTION THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1982-01-19 US claimed
US-4259947-A ISOTOPICALLY LABELED COMPOUNDS KOBRINSKY PETER C 1981-04-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030060487-A1 Treatment of neurodegenerative disease HTT, IAPP, APP TSHR 4189/4885CYP3A4 4876/4885NFKB1 3132/4885
US-20260002951-A1 METHOD FOR PROVIDING INFORMATION FOR BRAIN DOPING DIAGNOSIS COMT, HNMT, PNMT TSHR 1190/4885CYP3A4 464/4885NFKB1 4862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.