SCHEMBL4354033

SCHEMBL4354033

C#Cc1ccc(C(=O)Oc2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.54
TMPRSS15 P98073 2/20 0.53
PRSS1 P07477 1/20 0.53
ACR P10323 1/20 0.53
MAPT P10636 6/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NSD2 O96028 1/20 0.50
KMT2A Q03164 6/20 0.49
MEN1 O00255 3/20 0.49
ALDH1A1 P00352 5/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PKM P14618 1/20 0.47
ALOX5 P09917 1/20 0.45
RAB9A P51151 1/20 0.45
HPGD P15428 2/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165917 0.93 PARP10 (0.59) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL70034 0.84 PARP10 (0.70) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL4361160 0.84 PARP10 (0.56) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL8772500 0.84 PARP10 (0.56) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL19168001 0.84 PARP10 (0.56) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL28829041 0.83 PRSS1 (0.55) PRSS1ACRSMN1; SMN2KMT2AMEN1
SCHEMBL4814349 0.82 ALDH1A1 (0.58) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL21638941 0.82 PARP10 (0.54) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL10412434 0.82 PARP10 (0.54) PARP10TMPRSS15PRSS1ACRMAPT
SCHEMBL13692713 0.81 MAPT (0.51) PARP10PRSS1ACRMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402644-B Water-soluble active ester polymer and synthesis method and application thereof 苏州嘉佑生物科技有限公司 2022-09-06 CN claimed
CN-113402644-B Water-soluble active ester polymer and synthesis method and application thereof 苏州嘉佑生物科技有限公司 2022-09-06 CN disclosed
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
CN-100462389-C Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS INC (JP) 2009-02-18 CN disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
CN-1630676-A Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS INC (JP) 2005-06-22 CN disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed