Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | ACR | P10323 | 1/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5112141 | 0.93 | PARP10 (0.61) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL9069950 | 0.90 | HSD17B10 (0.53) | PARP10PRSS1ACRMAPTSMN1; SMN2 | |
| SCHEMBL70034 | 0.86 | PARP10 (0.70) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL4361160 | 0.85 | PARP10 (0.56) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL19168001 | 0.85 | PARP10 (0.56) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL4354033 | 0.84 | PARP10 (0.54) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL10412434 | 0.84 | PARP10 (0.54) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL4814349 | 0.84 | ALDH1A1 (0.58) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL8205435 | 0.82 | PARP10 (0.78) | PARP10TMPRSS15PRSS1ACRNSD2 | |
| SCHEMBL1870544 | 0.82 | PARP10 (0.70) | PARP10TMPRSS15PRSS1ACRNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |