SCHEMBL4354147

SCHEMBL4354147

O=C(Nc1ccccc1)OCC(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
LMNA P02545 3/20 0.55
NPSR1 Q6W5P4 3/20 0.55
S1PR2 O95136 1/20 0.55
S1PR4 O95977 1/20 0.55
GAA P10253 1/20 0.55
MAPT P10636 1/20 0.55
XBP1 P17861 1/20 0.55
HTT P42858 1/20 0.55
PAX8 Q06710 1/20 0.55
S1PR3 Q99500 1/20 0.55
S1PR5 Q9H228 1/20 0.55
NPC1 O15118 5/20 0.54
RAB9A P51151 5/20 0.54
TSHR P16473 1/20 0.54
RECQL P46063 1/20 0.53
MGLL Q99685 1/20 0.49
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL11483031 0.95 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL22418600 0.86 NPC1 (0.51) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL16660538 0.85 NPC1 (0.57) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL11150507 0.84 NPC1 (0.56) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL25506591 0.83 NPC1 (0.51) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL10591163 0.83 L3MBTL1 (0.51) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL26129952 0.83 NPC1 (0.59) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL12994523 0.82 NPC1 (0.48) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL14349237 0.82 RAB9A (0.54) SMN1; SMN2MEN1KMT2ALMNANPSR1
SCHEMBL10778464 0.82 NPC1 (0.54) SMN1; SMN2MEN1KMT2ALMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4693286-A1 PHOTOSENSITIVE COMPOSITION FOR HOLOGRAM RECORDING, HOLOGRAM RECORDING MEDIUM, POLYMER, LARGE CAPACITY MEMORY, OPTICAL ELEMENT, AR LIGHT GUIDE PLATE, AND AR GLASSES Mitsubishi Chemical Corporation (JP) 2026-02-11 EP disclosed
US-20260023321-A1 PHOTOSENSITIVE COMPOSITION FOR HOLOGRAM RECORDING, HOLOGRAM RECORDING MEDIUM, POLYMER, LARGE CAPACITY MEMORY, OPTICAL ELEMENT, AR LIGHT GUIDE PLATE, AND AR GLASSES MITSUBISHI CHEMICAL CORPORATION (JP) 2026-01-22 US disclosed
EP-4606785-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAM RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2025-08-27 EP disclosed
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2025-06-26 US disclosed
EP-4549430-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2025-05-07 EP disclosed
US-20250122178-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2025-04-17 US disclosed
WO-2024153147-A1 AZACYCLOALKANE COMPOUND AND PHARMACEUTICAL COMPOSITION, AND USE THEREOF 北京普祺医药科技股份有限公司 2024-07-25 WO disclosed
EP-4317155-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
US-20240018137-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-18 US disclosed
EP-4063356-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL AND OPTICAL COMPONENT Mitsubishi Chemical Corporation (JP) 2022-09-28 EP disclosed
EP-0110732-B1 PROCESS FOR PRODUCING DIPHENYLMETHANE DICARBAMATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-03-11 EP disclosed
EP-0123412-B1 METHOD FOR MANUFACTURE OF DIPHENYLMETHANE DIISOCYANATES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-07-09 EP disclosed
US-4552974-A Process for producing diphenylmethane dicarbamates ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-11-12 US disclosed
US-4547322-A Method for manufacture of diphenylmethane diisocyanates ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-10-15 US disclosed
EP-0123412-A1 Method for manufacture of diphenylmethane diisocyanates Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-10-31 EP disclosed
EP-0110732-A2 Process for producing diphenylmethane dicarbamates Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-06-13 EP disclosed
EP-0014103-B1 IMPROVED PROCESS FOR THE MANUFACTURE OF CARBAMATES THE HALCON SD GROUP, INC. (US) 1983-05-11 EP disclosed
US-4258201-A CATALYTIC CARBONYLATION OF PRIMARY OR SECONDARY AMINES WITH CARBON MONOXIDE AND ALCOHOLS HALCON RESEARCH AND DEVELOPMENT CORP. (US) 1981-03-24 US disclosed
US-4242520-A ONE-STEP CARBONYLATION OF AMINES IN THE PRESENCE OF A DISULFIDE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-12-30 US disclosed
EP-0014103-A2 Improved process for the manufacture of carbamates THE HALCON SD GROUP, INC. (US) 1980-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250206731-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT H1-0, H1-3, H1-2 SMN1; SMN2 2247/4885MEN1 2487/4885KMT2A 2460/4885
US-20250122178-A1 COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT H1-0, H1-2, CCNB2 SMN1; SMN2 1478/4885MEN1 1438/4885KMT2A 2821/4885
US-20240018137-A1 COMPOUND, METHOD FOR PRODUCING SAME, POLYMERIZABLE COMPOSITION, POLYMER, HOLOGRAPHIC RECORDING MEDIUM, OPTICAL MATERIAL, AND OPTICAL COMPONENT F12, SEM1, NOX1 SMN1; SMN2 1095/4885MEN1 776/4885KMT2A 2336/4885
US-20260023321-A1 PHOTOSENSITIVE COMPOSITION FOR HOLOGRAM RECORDING, HOLOGRAM RECORDING MEDIUM, POLYMER, LARGE CAPACITY MEMORY, OPTICAL ELEMENT, AR LIGHT GUIDE PLATE, AND AR GLASSES RAD51, NAP1L1, RPA1 SMN1; SMN2 437/4885MEN1 516/4885KMT2A 1136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.