Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.30 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.30 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350506 | 1.00 | CES2 (0.35) | CES2MAPTKDM4ETP53CYP3A4 | |
| SCHEMBL4354828 | 1.00 | CES2 (0.35) | CES2MAPTKDM4ETP53CYP3A4 | |
| SCHEMBL4356198 | 0.99 | CES2 (0.33) | CES2MAPTKDM4ETP53CYP3A4 | |
| SCHEMBL4345966 | 0.94 | CA1 (0.30) | — | |
| SCHEMBL4342571 | 0.88 | LMNA (0.32) | CYP3A4TSHRLMNA | |
| SCHEMBL4355377 | 0.83 | CES2 (0.35) | CES2MAPTLMNASMPD1ZDHHC7 | |
| SCHEMBL4350603 | 0.83 | CES2 (0.35) | CES2MAPTLMNASMPD1ZDHHC7 | |
| SCHEMBL4344813 | 0.83 | CES2 (0.35) | CES2MAPTLMNASMPD1ZDHHC7 | |
| SCHEMBL4351874 | 0.81 | CES2 (0.33) | CES2 | |
| SCHEMBL3912723 | 0.78 | CES2 (0.43) | CES2MAPTKDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090277559-A1 | METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2009-11-12 | — | — | US | disclosed |