Asparagine

Asparagine

SCHEMBL4354914

CC(N)C(=O)O.NC(=O)CC(N)C(=O)O.O=C(O)C1CCCN1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Asparagine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.37
NOS3 P29474 1/20 0.37
NOS1 P29475 1/20 0.37
GRIK1 P39086 4/20 0.36
GRIA2 P42262 2/20 0.36
GRIA4 P48058 2/20 0.36
GRIK3 Q13003 2/20 0.36
GRIK5 Q16478 2/20 0.36
GRIK2 Q13002 2/20 0.36
GRIA1 P42261 1/20 0.36
SLC7A5 Q01650 1/20 0.35
PRCP P42785 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Asparagine SCHEMBL537634 1.00 NOS2 (0.37) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL2440846 1.00 NOS2 (0.37) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL22654326 0.96 NOS2 (0.34) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL22654328 0.96 NOS2 (0.34) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL2537696 0.94 NOS2 (0.41) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL2484608 0.94 NOS2 (0.41) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL2537700 0.94 NOS2 (0.41) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL2484607 0.94 NOS2 (0.41) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL28801809 0.94 NOS2 (0.41) NOS2NOS3NOS1GRIK1GRIA2
Asparagine SCHEMBL28252029 0.94 NOS2 (0.41) NOS2NOS3NOS1GRIK1GRIA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190197332-A1 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES KAVANAU CHRISTOPHER L (US) 2019-06-27 US disclosed
US-10152643-B2 Method and system for aligning and classifying images Kavanau, Christopher L. (US) 2018-12-11 US disclosed
US-20180053065-A1 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES KAVANAU CHRISTOPHER L (US) 2018-02-22 US disclosed
US-9792518-B2 Method and system for aligning and classifying images Kavanau, Christopher L. (US) 2017-10-17 US disclosed
US-20170249523-A9 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES KAVANAU CHRISTOPHER L (US) 2017-08-31 US disclosed
US-20160070969-A1 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES KAVANAU CHRISTOPHER L (US) 2016-03-10 US disclosed
US-9064188-B2 Method and system for aligning and classifying images Kavanau, Christopher L. (US) 2015-06-23 US disclosed
US-20140072207-A1 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES Kavanau, Christopher L. (US) 2014-03-13 US disclosed
US-8503825-B2 Method and system for aligning and classifying images Kavanau, Christopher L. (US) 2013-08-06 US disclosed
US-20090274375-A1 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-11-05 US disclosed
EP-1751696-A2 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES The Regents of the University of California (US) 2007-02-14 EP disclosed
WO-2005117541-A2 METHOD AND SYSTEM FOR ALIGNING AND CLASSIFYING IMAGES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-12-15 WO disclosed