Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889763 | 0.83 | THRB (0.42) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL18871677 | 0.82 | HSD17B10 (0.43) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL1457731 | 0.81 | THRB (0.52) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL3986078 | 0.81 | LMNA (0.43) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL11397275 | 0.81 | THRB (0.47) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL27082403 | 0.81 | THRB (0.52) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL7815397 | 0.80 | LMNA (0.54) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL9786146 | 0.79 | THRB (0.59) | THRBALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL11451272 | 0.79 | TSHR (0.39) | THRBALDH1A1HTTKMT2AHSD17B10 | |
| SCHEMBL94118 | 0.79 | KLK1 (0.45) | THRBALDH1A1KMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116893235-A | Method and kit for determining polychlorinated biphenyl and multi-class brominated flame retardant residues in traditional Chinese medicine | 江苏省食品药品监督检验研究院(江苏省食品质量安全监控中心) | 2023-10-17 | — | — | CN | claimed |
| CN-116554658-A | Preparation method of high-performance flame-retardant recycled bottle flake PET plastic | 安徽荣繁盛新材料科技有限公司 | 2023-08-08 | — | — | CN | claimed |
| CN-111892795-B | ABS material for magnetic sheet toy and preparation method thereof | 杭州思创磁性器件有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-113956384-A | Preparation method of efficient flame-retardant polystyrene resin | 南京越升挤出机械有限公司 | 2022-01-21 | — | — | CN | claimed |
| CN-110408132-B | Graphene/butyl rubber composite master batch and preparation method of composite material | 成都创威新材料有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-109929245-B | High-air-tightness PPA composite material and preparation method thereof | 广东京兆工程塑料有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-112206457-A | Biomass gel-based dry water powder extinguishing agent and preparation method thereof | 武汉理工大学 | 2021-01-12 | — | — | CN | claimed |
| CN-111892795-A | ABS material for magnetic sheet toy and preparation method thereof | 杭州思创磁性器件有限公司 | 2020-11-06 | — | — | CN | claimed |
| CN-111534060-A | Reinforced flame-retardant PBT/PET alloy and preparation method thereof | 浙江钧科新材料有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-106147086-A | A kind of fluorubber/graphene composite material and preparation method thereof | 成都创威新材料有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-106117681-A | A kind of neoprene/graphene composite material and preparation method thereof | 成都创威新材料有限公司 | 2016-11-16 | — | — | CN | claimed |
| CN-104059321-A | Weather-proof environment-friendly flame-retardant polymer material for flexible cable and preparation method thereof | SINOTEX INVEST & DEV CO LTD | 2014-09-24 | — | — | CN | claimed |
| CN-101665555-B | Method for preparing continuous bulk of flame retardant and highly impact resistant acrylonitrile-chlorinated polyethylene-styrene resin | NINGBO OCEANKING CHEMICAL DEV CO LTD | 2013-07-03 | — | — | CN | claimed |
| CN-101665555-A | Method for preparing continuous bulk of flame retardant and highly impact resistant acrylonitrile-chlorinated polyethylene-styrene resin | NINGBO OCEANKING CHEMICAL DEV | 2010-03-10 | — | — | CN | claimed |
| EP-0129824-B1 | FLAME RETARDANT BLENDS OF ABS RESIN AND POLYPHENYLENE ETHER | GENERAL ELECTRIC COMPANY (US) | 1992-12-09 | — | — | EP | claimed |
| US-4945018-A | WIRE AND CABLE INSULATION, PHOSPHATE OR PHOSPHONATE COMPOUND | GENERAL ELECTRIC COMPANY (US) | 1990-07-31 | — | — | US | claimed |
| US-4073772-A | BISPHENOXY FLAME RETARDANT | VELSICOL CHEMICAL CORPORATION (US) | 1978-02-14 | — | — | US | claimed |
| US-12071418-B2 | Processes for preparation of dapagliflozin or its solvates or co-crystals thereof | LAURUS LABS LIMITED (IN) | 2024-08-27 | — | — | US | disclosed |
| US-4033932-A | BIS-PHENOXY COMPOUNDS | VELSICOL CHEMICAL CORPORATION (US) | 1977-07-05 | — | — | US | disclosed |
| US-4032508-A | POLYSTYRENE AND A BISPENTABROMOPHENOXY ALKANE AS FLAME RETARDANT | VELSICOL CHEMICAL CORPORATION (US) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12071418-B2 | Processes for preparation of dapagliflozin or its solvates or co-crystals thereof | SLC5A1, SLC5A2, SLC2A4 | THRB 3723/4885ALDH1A1 1889/4885HTT 3636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.