Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636085 | 0.83 | SLC6A4 (0.53) | SLC6A4DRD2ADRA1DIDO1HTR2A | |
| SCHEMBL30275187 | 0.82 | HTR2A (0.64) | SLC6A4DRD2ADRA1DIDO1HTR2A | |
| SCHEMBL2904310 | 0.82 | HTR2A (0.64) | SLC6A4DRD2ADRA1DIDO1HTR2A | |
| Hydrochloric Acid SCHEMBL6248133 | 0.81 | HTR2C (0.63) | SLC6A4DRD2ADRA1DIDO1HTR2A | |
| SCHEMBL4671007 | 0.81 | SLC6A4 (0.59) | SLC6A4DRD2ADRA1DIDO1HTR2A | |
| Bromide SCHEMBL7870891 | 0.80 | DRD2 (0.73) | SLC6A4DRD2ADRA1DHTR2AOPRM1 | |
| Hydrochloric Acid SCHEMBL7867314 | 0.80 | DRD2 (0.73) | SLC6A4DRD2ADRA1DHTR2AOPRM1 | |
| SCHEMBL6636763 | 0.79 | DRD2 (0.57) | SLC6A4DRD2ADRA1DIDO1HTR2A | |
| SCHEMBL31295173 | 0.78 | HTR2A (0.59) | SLC6A4DRD2ADRA1DIDO1HTR2A | |
| Ethylene SCHEMBL7483250 | 0.77 | DRD2 (0.55) | SLC6A4DRD2ADRA1DIDO1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528230-A | Indoloquinoline compounds as calcium channel blockers | MEDIPROPHARMA INC (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-2063891-A2 | INDOLOQUINOLINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Medipropharma, Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008027182-A2 | INDOLOQUINOLINE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | MEDIPROPHARMA, INC. (US) | 2008-03-06 | — | — | WO | disclosed |