Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | CA4 | P22748 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL29401074 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL1229932 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL15362198 | 1.00 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL118974 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29397605 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL29397432 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL28619730 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL975525 | 0.96 | TP53 (0.50) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL25270068 | 0.93 | — | — | |
| L-Lactic Acid SCHEMBL8462013 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170209489-A1 | FAST ACTING INHIBITOR OF GASTRIC ACID SECRETION WITH ENHANCED ACTIVITY | UNIV YALE (US) | 2017-07-27 | — | — | US | claimed |
| WO-2015153552-A1 | FAST ACTING INHIBITOR OF GASTRIC ACID SECRETION WITH ENHANCED ACTIVITY | YALE UNIVERSITY (US) | 2015-10-08 | — | — | WO | claimed |
| EP-1602685-B1 | Pressing granulated fire retardant composition | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2011-02-02 | — | — | EP | claimed |
| WO-2004080210-A1 | COMPOSITIONS OF DIETARY METALS FOR SUPPORT OF THE PHYSIOLOGICAL INTESTINAL DEVELOPMENT AND PREVENTION OF DIARRHOEA | BOEHRINGER INGELHEIM DANMARK A/S (DK) | 2004-09-23 | — | — | WO | claimed |
| EP-4017462-B1 | ORAL CARE COMPOSITIONS CONTAINING INULIN | COLGATE PALMOLIVE CO (US) | 2026-04-01 | — | — | EP | disclosed |
| US-12318463-B2 | Compositions and methods for treating canker sores | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-06-03 | — | — | US | disclosed |
| WO-2025089221-A1 | COMPOSITION, MOLDED BODY, FILM, AND LAYERED STRUCTURE | 三菱ケミカル株式会社 | 2025-05-01 | — | — | WO | disclosed |
| EP-3810067-B1 | METHODS OF INHIBITING MICROBIAL INFECTIONS USING ZINC-CONTAINING COMPOSITIONS | TRIUMPH PHARMACEUTICALS INC (US) | 2025-04-16 | — | — | EP | disclosed |
| US-20250049659-A1 | ORAL COMPOSITIONS AND METHODS OF REDUCING ORAL MALODOR | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2025-02-13 | — | — | US | disclosed |
| US-20250041196-A1 | Oral Care Compositions with Hyaluronic Acid | COLGATE-PALMOLIVE COMPANY (US) | 2025-02-06 | — | — | US | disclosed |
| US-12053485-B2 | Methods of inhibiting microbial infections using zinc-containing compositions | TRIUMPH PHARMACEUTICALS INC. (US) | 2024-08-06 | — | — | US | disclosed |
| CN-118369083-A | Oral care compositions with hyaluronic acid | 高露洁-棕榄公司 | 2024-07-19 | — | — | CN | disclosed |
| US-20050143503-A1 | Phosphorus-containing flame retardant agglomerates | CLARIANT GMBH | 2005-06-30 | — | — | US | disclosed |
| US-20050137418-A1 | Process for preparation of dialkylphosphinic salts | CLARIANT GMBH | 2005-06-23 | — | — | US | disclosed |
| WO-2004080210-A1 | COMPOSITIONS OF DIETARY METALS FOR SUPPORT OF THE PHYSIOLOGICAL INTESTINAL DEVELOPMENT AND PREVENTION OF DIARRHOEA | BOEHRINGER INGELHEIM DANMARK A/S (DK) | 2004-09-23 | — | — | WO | disclosed |
| EP-0768277-B1 | FINE ZINC OXIDE PARTICLES, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | NIPPON CATALYTIC CHEM IND (JP) | 2002-10-02 | — | — | EP | disclosed |
| US-6200680-B1 | COMPRISING A METAL OXIDE COPRECIPITATE OF ZINC AND A METAL OF GROUP 3 OR 4 HAVING A ZINC CONTENT OF 80-99.9% ZINC ATOMS AND HAVING X-RAY CRYSTALLOGRAPHICALLY EXHIBITING ZINC OXIDE CRYSTALLINE PROPERTIES; COSMETICS; PAPER COATINGS; DRUGS | NIPPON SHOKUBAI CO., LTD. (JP) | 2001-03-13 | — | — | US | disclosed |
| EP-0893409-A1 | Zinc oxide-based fine particles, process for producing the same, and use thereof | NIPPON SHOKUBAI CO., LTD. (JP) | 1999-01-27 | — | — | EP | disclosed |
| US-5696169-A | CONTAINING A ZINC COMPOUND AND HINOKITIOL | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0768277-A1 | FINE ZINC OXIDE PARTICLES, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | NIPPON SHOKUBAI KAGAKU KOGYO CO. LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |