SCHEMBL4355030

SCHEMBL4355030

O=C(OC(O)CO)c1ccccc1C(=O)OC(O)CO

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.46
TSHR P16473 6/20 0.46
CYP3A4 P08684 3/20 0.41
NPC1 O15118 2/20 0.41
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
TP53 P04637 1/20 0.39
MAPK1 P28482 1/20 0.39
SCN1A P35498 1/20 0.39
SCN2A Q99250 1/20 0.39
SCN3A Q9NY46 1/20 0.39
LMNA P02545 1/20 0.38
PRKCA P17252 1/20 0.37
CA2 P00918 1/20 0.37
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28925252 0.93 ALDH1A1 (0.50) ALDH1A1TSHRSCN1ASCN2ASCN3A
SCHEMBL29080984 0.84 ALDH1A1 (0.43) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL28347679 0.82 PTGS2 (0.56) ALDH1A1TSHRTDP1MAPK1LMNA
SCHEMBL1513963 0.82 TSHR (0.53) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL27821840 0.82 TSHR (0.57) ALDH1A1TSHRNPC1TDP1TP53
SCHEMBL28240740 0.81 ALDH1A1 (0.43) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL28446203 0.81 TSHR (0.41) ALDH1A1TSHRCYP3A4NPC1TDP1
SCHEMBL1513875 0.79 ALDH1A1 (0.52) ALDH1A1TSHRCYP3A4TDP1L3MBTL1
SCHEMBL17830011 0.78 BCHE (0.33) ALDH1A1TSHRSCN1ASCN2ASCN3A
SCHEMBL5693883 0.78 CYP4A11 (0.47) ALDH1A1TSHRNPC1TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113396145-A PFKFB3 inhibitors and uses thereof 盖罗发现有限责任公司 2021-09-14 CN disclosed
EP-1471387-B1 Photosensitive composition and compound used thereof FUJIFILM CORP (JP) 2015-11-11 EP disclosed
US-8211598-B2 Black photosensitive resin composition, and color filter and method of producing the same FUJIFILM CORPORATION (JP) 2012-07-03 US disclosed
EP-2120094-A2 Black photosensitive resin composition, and color filter and method of producing the same Fujifilm Corporation (JP) 2009-11-18 EP disclosed
US-20090280416-A1 BLACK PHOTOSENSITIVE RESIN COMPOSITION, AND COLOR FILTER AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2009-11-12 US disclosed
EP-1467250-B1 Photosensitive composition and litographic printing plate precursor FUJIFILM CORP (JP) 2008-10-22 EP disclosed
US-7267925-B2 Photosensitive composition and novel compound used therefor FUJIFILM CORPORATION (JP) 2007-09-11 US disclosed
EP-1471387-A2 Photosensitive composition and compound used thereof FUJI PHOTO FILM CO., LTD. (JP) 2004-10-27 EP disclosed
US-20040202957-A1 Photosensitive composition and lithographic printing plate precursor using the same FUJI PHOTO FILM CO., LTD. 2004-10-14 US disclosed
EP-1467250-A2 Photosensitive composition and litographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2004-10-13 EP disclosed
US-20040191679-A1 Photosensitive composition and novel compound used therefor FUJI PHOTO FILM CO., LTD. 2004-09-30 US disclosed
US-4985324-A TETRAKISAZO CHARGE GENERATING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1991-01-15 US disclosed
US-4882249-A PHOTOSENSITIVITY, DURABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-11-21 US disclosed
US-4871637-A DURABILITY, PHOTOSENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed