Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.33 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RHEB | Q15382 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8671624 | 0.88 | RECQL (0.41) | RECQLLMNAALDH1A1UGT2B7HPGD | |
| SCHEMBL3414680 | 0.81 | KIF11 (0.35) | POLBALDH1A1NCEH1CYP1A2 | |
| SCHEMBL28172974 | 0.79 | CYP3A4 (0.39) | RECQLLMNAALDH1A1UGT2B7HPGD | |
| SCHEMBL18910955 | 0.75 | ALDH1A1 (0.48) | LMNAALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL8376182 | 0.75 | UGT2B7 (0.50) | RECQLPOLBLMNAUGT2B7TSHR | |
| SCHEMBL17539919 | 0.74 | TSHR (0.41) | LMNAALDH1A1HPGDTSHRGAA | |
| SCHEMBL18905343 | 0.74 | ALDH1A1 (0.33) | RECQLLMNAALDH1A1HPGDTSHR | |
| SCHEMBL28511 | 0.74 | ALDH1A1 (0.44) | POLBALDH1A1TSHRMAPK1GAA | |
| SCHEMBL29352635 | 0.74 | ALDH1A1 (0.44) | POLBALDH1A1TSHRMAPK1GAA | |
| SCHEMBL240650 | 0.73 | UGT2B7 (0.47) | POLBALDH1A1UGT2B7HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635571-B2 | photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20040175696-A1 | Amplified luminescent homogeneous immunoassay | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2004-09-09 | — | — | US | disclosed |