Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15800600 | 0.95 | POLB (0.50) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL11706062 | 0.88 | POLB (0.47) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL25801655 | 0.86 | CYP3A4 (0.51) | POLBCYP3A4CYP2D6NPSR1TSHR | |
| SCHEMBL9649565 | 0.84 | POLB (0.44) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL9649575 | 0.84 | POLB (0.44) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL10687870 | 0.82 | NQO1 (0.50) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL9648262 | 0.82 | POLB (0.43) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL9648269 | 0.82 | POLB (0.43) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL9650096 | 0.81 | POLB (0.42) | POLBCYP3A4CYP2D6NPSR1NQO1 | |
| SCHEMBL9650101 | 0.81 | POLB (0.42) | POLBCYP3A4CYP2D6NPSR1NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312558-A1 | PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPOANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-12-17 | — | — | US | disclosed |
| WO-2009150660-A1 | A PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-12-17 | — | — | WO | disclosed |
| US-5248834-A | Pesticides | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1993-09-28 | — | — | US | disclosed |
| EP-0179788-B1 | PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1991-06-12 | — | — | EP | disclosed |
| US-4859232-A | Substituted-aryl cyclopropanecarbonitriles and derivatives thereof as herbicide antidotes | MONSANTO COMPANY (US) | 1989-08-22 | — | — | US | disclosed |
| US-4777185-A | Phenyl phenoxyphenyl propenyl cyclopropane pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-10-11 | — | — | US | disclosed |
| US-4713392-A | Pesticides | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-12-15 | — | — | US | disclosed |
| EP-0179788-A1 | PESTICIDES. | NAT RES DEV (GB) | 1986-05-07 | — | — | EP | disclosed |
| EP-0161921-A2 | Improvements relating to pesticides | BTG INTERNATIONAL LIMITED (GB) | 1985-11-21 | — | — | EP | disclosed |
| WO-1985004651-A1 | IMPROVEMENTS RELATING TO PESTICIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1985-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312558-A1 | PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPOANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | NOTUM, SULT2A1, SULT1A1 | POLB 2803/4885CYP3A4 98/4885CYP2D6 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.