Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9555462 | 0.88 | L3MBTL1 (0.50) | TLR7L3MBTL1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL4350914 | 0.84 | HDAC1 (0.51) | TLR7L3MBTL1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL1829195 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTLMNAGAAKDM4E | |
| SCHEMBL4355343 | 0.78 | TLR7 (0.64) | TLR7L3MBTL1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL11102756 | 0.78 | CYP19A1 (0.47) | L3MBTL1SMN1; SMN2MAPTLMNAGAA | |
| SCHEMBL2928098 | 0.76 | HPGD (0.49) | SMN1; SMN2MAPTKMT2ALMNAKDM4E | |
| SCHEMBL9555459 | 0.76 | KDM4E (0.71) | TLR7L3MBTL1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL369872 | 0.76 | CYP19A1 (0.59) | TLR7MAPTGAAKDM4EALDH1A1 | |
| SCHEMBL3057919 | 0.75 | TLR7 (0.64) | TLR7L3MBTL1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL12171802 | 0.74 | CYP19A1 (0.67) | L3MBTL1SMN1; SMN2MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070916-A1 | 2-Arylthiazol-4-carboxylic acid derivatives, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |