Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HPGDS | O60760 | 1/20 | 0.57 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3057919 | 0.88 | TLR7 (0.64) | TLR7ALDH1A1L3MBTL1MAPTATM | |
| SCHEMBL2555429 | 0.83 | TLR7 (0.70) | TLR7ALDH1A1L3MBTL1MAPTATM | |
| SCHEMBL352152 | 0.82 | HPGDS (0.73) | TLR7ALDH1A1L3MBTL1MAPTATM | |
| SCHEMBL6182649 | 0.82 | HPGDS (0.57) | ALDH1A1KDM4EHPGDSTDP1PLA2G10 | |
| SCHEMBL3353616 | 0.82 | ALDH1A1 (0.68) | ALDH1A1KDM4EHPGDSKMOPLA2G10 | |
| SCHEMBL31351171 | 0.82 | KDM4E (0.66) | TLR7ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL2551944 | 0.82 | TLR7 (0.63) | TLR7ALDH1A1KDM4EHPGDSTDP1 | |
| SCHEMBL3412110 | 0.81 | ALDH1A1 (0.71) | TLR7ALDH1A1L3MBTL1MAPTATM | |
| Hydrochloric Acid SCHEMBL6821751 | 0.80 | HPGDS (0.71) | TLR7ALDH1A1L3MBTL1MAPTATM | |
| SCHEMBL12171802 | 0.80 | CYP19A1 (0.67) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2022-06-30 | — | — | US | disclosed |
| EP-2070916-A1 | 2-Arylthiazol-4-carboxylic acid derivatives, their manufacture and use as medicine | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220202772-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RIBOSOME INACTIVATING PROTEINS | RACK1, RRBP1, RPL30 | TLR7 4701/4885ALDH1A1 3524/4885L3MBTL1 156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.