Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347324 | 0.82 | POLB (0.51) | POLBMEN1KMT2AHRH3CYP2D6 | |
| SCHEMBL2156044 | 0.81 | ALDH1A1 (0.61) | ALDH1A1POLBNAMPTMEN1KMT2A | |
| SCHEMBL23388092 | 0.81 | HPGD (0.48) | ALDH1A1POLBMEN1KMT2AHTT | |
| SCHEMBL743014 | 0.81 | HPGD (0.53) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL2536712 | 0.79 | HPGD (0.56) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL15107941 | 0.78 | ALDH1A1 (0.58) | ALDH1A1POLBNAMPTHRH3KDM4E | |
| SCHEMBL2342799 | 0.78 | KMT2A (0.56) | ALDH1A1POLBMEN1KMT2AHRH3 | |
| SCHEMBL743882 | 0.77 | SMN1; SMN2 (0.57) | ALDH1A1POLBKMT2AHTTKDM4E | |
| SCHEMBL23387920 | 0.77 | HPGD (0.51) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL23388061 | 0.75 | GRM5 (0.47) | NAMPTHTTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |