SCHEMBL4356077

SCHEMBL4356077

CCO[Si](CCC(C)OCC1CO1)(OCC)OCC.CO[Si](CCCCOCC1CO1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446854 0.84 TSHR (0.55) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL1920460 0.84 SMN1; SMN2 (0.53) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL6063082 0.84 TSHR (0.55) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL188483 0.84 ALDH1A1 (0.33) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL22472012 0.83 ALDH1A1 (0.33) ALDH1A1TDP1SMN1; SMN2
SCHEMBL188319 0.83 TSHR (0.60) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL10590092 0.83 TSHR (0.60) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL7542607 0.81 SMN1; SMN2 (0.50) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL23706415 0.81 ALDH1A1 (0.62) ALDH1A1TDP1TSHRSMN1; SMN2
SCHEMBL23706418 0.81 ALDH1A1 (0.62) ALDH1A1TDP1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138501-B1 Functional silane compound, coating solution, and method for manufacturing plastic lens HOYA CORP (JP) 2014-08-13 EP disclosed
EP-2138501-A2 Functional silane compound, coating solution, and method for manufacturing plastic lens Hoya Corporation (JP) 2009-12-30 EP disclosed