Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | ADK | P55263 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.43 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13019018 | 0.87 | PIK3CG (0.50) | PIK3CGPI4KAPI4K2BPI4K2API4KB | |
| Sulfuric Acid SCHEMBL3740961 | 0.81 | PIK3CG (0.47) | PIK3CGPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL3742316 | 0.78 | ADK (0.76) | PIK3CGPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12014918 | 0.73 | MCL1 (0.38) | PI4KAPI4K2BPI4K2API4KBKDM4E | |
| SCHEMBL16597187 | 0.73 | KDM4E (0.56) | PI4KAPI4K2BPI4K2API4KBADK | |
| SCHEMBL323086 | 0.72 | KDM4E (0.68) | KDM4ENPC1ULK1CDK7CDK5 | |
| SCHEMBL6761875 | 0.70 | KDM4E (0.53) | KDM4ENPC1ULK1CDK7CDK5 | |
| SCHEMBL3532692 | 0.69 | PIK3CG (1.00) | PIK3CGPI4KBADKDYRK1ARPS6KA1 | |
| SCHEMBL13019047 | 0.69 | KDM4E (0.53) | KDM4ENPC1ULK1CDK7CDK5 | |
| SCHEMBL12763675 | 0.68 | KDM4E (0.54) | KDM4ENPC1ULK1CDK7CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039683-B1 | Vasculostatic agents and methods of use thereof | TARGEGEN INC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2039683-A2 | Vasculostatic agents and methods of use thereof | Targegen, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |