SCHEMBL4356412 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	SLC6A2	P23975	1/20	0.37

▸	SLC6A4	P31645	1/20	0.37

▸	SLC6A3	Q01959	1/20	0.37

▸	PTGS2	P35354	9/20	0.36

▸	PLAT	P00750	1/20	0.36

▸	DPP4	P27487	1/20	0.34

▸	PIK3CA	P42336	1/20	0.33

▸	HRH3	Q9Y5N1	1/20	0.33

▸	WNT3A	P56704	1/20	0.33

▸	TNKS2	Q9H2K2	1/20	0.33

▸	SIRT2	Q8IXJ6	1/20	0.33

▸	USP30	Q70CQ3	1/20	0.33

▸	PNMT	P11086	1/20	0.33

▸	FAAH	O00519	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL4347925	0.82	USP30 (0.40)	SLC6A2SLC6A4SLC6A3PTGS2DPP4
SCHEMBL9936211	0.81	GPR119 (0.45)	SLC6A2SLC6A4SLC6A3PTGS2PLAT
Hydrochloric Acid SCHEMBL15007649	0.81	GPR119 (0.45)	SLC6A2SLC6A4SLC6A3PTGS2PLAT
SCHEMBL4349922	0.80	PTPN2 (0.43)	PIK3CA
SCHEMBL4356473	0.80	PTPN2 (0.43)	PIK3CA
SCHEMBL4537918	0.80	PTPN2 (0.43)	PIK3CA
SCHEMBL4534568	0.80	CA12 (0.39)	PTGS2PIK3CAUSP30
SCHEMBL4347874	0.79	KDM1A (0.41)	PIK3CAUSP30
SCHEMBL4353588	0.79	PIK3CA (0.43)	PIK3CAUSP30
SCHEMBL13586047	0.79	CYP1A2 (0.43)	HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009150144-A1	NEW GPR119MODULATORS	INOVACIA AB (SE)	2009-12-17	—	—	WO	disclosed
WO-2009150144-A1	NEW GPR119MODULATORS	INOVACIA AB (SE)	2009-12-17	—	—	WO	disclosed