Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | ADAMTS7 | Q9UKP4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356473 | 1.00 | PTPN2 (0.43) | PTPN2PTPN1PIK3CALMNASMN1; SMN2 | |
| SCHEMBL4537918 | 1.00 | PTPN2 (0.43) | PTPN2PTPN1PIK3CALMNASMN1; SMN2 | |
| SCHEMBL4360055 | 0.93 | ALDH1A1 (0.40) | PTPN2PTPN1PIK3CALMNASMN1; SMN2 | |
| SCHEMBL4353588 | 0.92 | PIK3CA (0.43) | PIK3CALMNACYP3A4SLC9A1 | |
| SCHEMBL4362452 | 0.91 | EPHX2 (0.37) | PTPN2PTPN1PIK3CALMNASMN1; SMN2 | |
| SCHEMBL4347963 | 0.90 | NPC1 (0.46) | PIK3CALMNAHTTALDH1A1CA12 | |
| SCHEMBL4347925 | 0.89 | USP30 (0.40) | PIK3CA | |
| SCHEMBL13586033 | 0.89 | LMNA (0.45) | PIK3CALMNASMN1; SMN2CYP2C19SLC9A1 | |
| SCHEMBL4355152 | 0.88 | CHRM2 (0.38) | PIK3CALMNASMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL4347838 | 0.88 | NAMPT (0.44) | PIK3CALMNASMN1; SMN2HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |