Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.62 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700123 | 1.00 | KDM4E (0.66) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL435677 | 0.92 | KMT2A (0.74) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10890390 | 0.89 | KMT2A (0.65) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11547023 | 0.89 | KMT2A (0.65) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL10890387 | 0.89 | KMT2A (0.65) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL3519648 | 0.87 | KMT2A (0.68) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11546170 | 0.86 | KMT2A (0.85) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9788399 | 0.86 | MAPT (0.85) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL9297690 | 0.86 | KMT2A (0.61) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11546161 | 0.86 | KMT2A (0.85) | KDM4EALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348618-B1 | PREPARING ORGANOLEPTIC OR ANTIMICROBIAL COMPOUNDS BY CONTACTING BETA-KETO ESTER WITH MATERIAL SELECTED FROM BACTERIA, ENZYMES, AND MATERIAL HAVING ACIDIC OR ALKALINE PH, ELEVATING TEMPERATURE, EXPOSING TO LIGHT | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2002-02-19 | — | — | US | disclosed |
| US-6222062-B1 | USEFUL AS PRECURSORS FOR ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES AND MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS | GIVAUDAN ROURE (INTERNATIONAL) SA (CH) | 2001-04-24 | — | — | US | disclosed |
| EP-1090624-A2 | Beta ketoester | Givaudan SA (CH) | 2001-04-11 | — | — | EP | disclosed |
| US-5951841-A | ACIDIC ELECTROPLATING BATHS COMPRISING BRIGHTENERS FOR THE ELECTROLYTIC DEPOSITION OF METALLIC INORGANIC LAYERS ONTO SHAPED ARTICLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-14 | — | — | US | disclosed |
| EP-0911315-A1 | Beta-ketoester | Givaudan Roure (International) S.A. (CH) | 1999-04-28 | — | — | EP | disclosed |