Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL2529015 | 0.92 | FDPS (0.46) | FDPSAKR1B1GPR84PPARGPPARD | |
| Bicarbonate SCHEMBL28711950 | 0.90 | GPR84 (0.52) | FDPSGPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL28426178 | 0.90 | GPR84 (0.52) | FDPSGPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL829821 | 0.90 | GPR84 (0.52) | FDPSGPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL3271999 | 0.90 | GPR84 (0.52) | FDPSGPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL9751030 | 0.90 | GPR84 (0.52) | FDPSGPR84PPARGPPARDPPARA | |
| Pivalate SCHEMBL4924833 | 0.88 | FDPS (0.43) | FDPSAKR1B1GPR84PPARGPPARD | |
| SCHEMBL2230483 | 0.86 | FDPS (0.42) | FDPSAKR1B1GPR84PPARGPPARD | |
| Dimethylcarbate SCHEMBL28644774 | 0.86 | FDPS (0.42) | FDPSAKR1B1GPR84PPARGPPARD | |
| SCHEMBL93609 | 0.86 | FDPS (0.46) | FDPSTSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | claimed |
| CN-119219550-A | Reduction method of carboxylic ester compound | 云南大学 | 2024-12-31 | — | — | CN | claimed |
| CN-115057867-B | Electrochromic compound, device, preparation method and application thereof | 吉林大学 | 2023-09-15 | — | — | CN | claimed |
| CN-113501779-B | Method for selectively removing benzyl, allyl and propargyl protecting groups by visible light or near visible light | 云南大学 | 2023-06-23 | — | — | CN | claimed |
| CN-115057867-A | Electrochromic compound, device, preparation method and application thereof | 吉林大学 | 2022-09-16 | — | — | CN | claimed |
| CN-115010836-A | Electrochromatic polymer, nano particles and device | 吉林大学 | 2022-09-06 | — | — | CN | claimed |
| CN-107710462-B | Electrochemical hydrogen storage electrode and battery | 巴斯夫公司 | 2022-08-02 | — | — | CN | claimed |
| CN-109504015-B | Electrochromic polymer material based on combination strategy and preparation of electrochromic device | 常州铱视光电科技有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-108795407-B | Electrochromic material based on action of electrochromic acid and preparation of electrochromic device | 常州铱视光电科技有限公司 | 2021-04-16 | — | — | CN | claimed |
| CN-108949141-B | Preparation method of bistable electrochromic material and application of bistable electrochromic material in preparation of electrochromic device | 常州铱视光电科技有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-111117594-A | Electrochromic material based on dynamic metal-ligand complexation and electrochromic device | 吉林大学 | 2020-05-08 | — | — | CN | claimed |
| CN-111039910-A | Photoinitiated method for synthesizing 3-aryl flavone or coumarin compound and application thereof | 云南大学 | 2020-04-21 | — | — | CN | claimed |
| CN-120058450-A | C (sp) in benzene ring2) Method for deuteration of the H bond | 云南大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-111117594-B | Electrochromic material and electrochromic device based on dynamic metal-ligand complexation | 吉林大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116997641-A | Substrate treating liquid, method for manufacturing substrate using the same, and method for manufacturing device | 默克专利有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-115057867-B | Electrochromic compound, device, preparation method and application thereof | 吉林大学 | 2023-09-15 | — | — | CN | disclosed |
| EP-2033257-A4 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | GEORGIA TECH RES INST (US) | 2009-07-01 | — | — | EP | disclosed |
| EP-2033257-A2 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | Georgia Tech Research Corporation (US) | 2009-03-11 | — | — | EP | disclosed |
| WO-2008054858-A2 | ANIONIC FUEL CELLS, HYBRID FUEL CELLS, AND METHODS OF FABRICATION THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2008-05-08 | — | — | WO | disclosed |
| US-20070259236-A1 | Anionic fuel cells, hybrid fuel cells, and methods of fabrication thereof | ENERGY, UNITED STATES DEPARTMENT OF | 2007-11-08 | — | — | US | disclosed |