Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.49 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.49 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.49 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436324 | 0.86 | PIK3CD (0.55) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| Hydrochloric Acid SCHEMBL435504 | 0.85 | PIK3CD (0.54) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL21301608 | 0.83 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL8257887 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL4232068 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL4232065 | 0.81 | PIK3CD (0.49) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL49798 | 0.81 | PIK3CD (0.58) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL4233323 | 0.80 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| SCHEMBL4233326 | 0.80 | PIK3CD (0.52) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB | |
| Hydrochlorthiazide SCHEMBL459506 | 0.80 | PIK3CD (0.48) | PIK3CDPIK3CGPIK3CAPIK3CBPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153389-B2 | Methods for the identification of PI3K interacting molecules and for the purification of PI3K | Cellzone AG (DE) | 2012-04-10 | — | — | US | disclosed |
| US-8153389-B2 | Methods for the identification of PI3K interacting molecules and for the purification of PI3K | Cellzone AG (DE) | 2012-04-10 | — | — | US | disclosed |
| EP-2410062-A1 | Selectivity profiling of PI3K interacting molecules against multiple targets | CELLZOME AG (DE) | 2012-01-25 | — | — | EP | disclosed |
| EP-2410062-A1 | Selectivity profiling of PI3K interacting molecules against multiple targets | CELLZOME AG (DE) | 2012-01-25 | — | — | EP | disclosed |
| EP-2245181-B1 | SELECTIVITY PROFILING OF PI3K INTERACTING MOLECULES AGAINST MULTIPLE TARGETS | CELLZOME AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| EP-2245181-B1 | SELECTIVITY PROFILING OF PI3K INTERACTING MOLECULES AGAINST MULTIPLE TARGETS | CELLZOME AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-20110111972-A1 | SELECTIVITY PROFILING OF PI3K INTERACTING MOLECULES AGAINST MULTIPLE TARGETS | CELLZOME AG (DE) | 2011-05-12 | — | — | US | disclosed |
| US-20110111972-A1 | SELECTIVITY PROFILING OF PI3K INTERACTING MOLECULES AGAINST MULTIPLE TARGETS | CELLZOME AG (DE) | 2011-05-12 | — | — | US | disclosed |
| EP-2245181-A1 | SELECTIVITY PROFILING OF PI3K INTERACTING MOLECULES AGAINST MULTIPLE TARGETS | CELLZOME AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| US-20100055711-A1 | METHODS FOR THE IDENTIFICATION OF PI3K INTERACTING MOLECULES AND FOR THE PURIFICATION OF PI3K | CELLZOME AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-20100055711-A1 | METHODS FOR THE IDENTIFICATION OF PI3K INTERACTING MOLECULES AND FOR THE PURIFICATION OF PI3K | CELLZOME AG (DE) | 2010-03-04 | — | — | US | disclosed |
| WO-2009098021-A1 | SELECTIVITY PROFILING OF PI3K INTERACTING MOLECULES AGAINST MULTIPLE TARGETS | CELLZOME AG (DE) | 2009-08-13 | — | — | WO | disclosed |
| EP-1887359-B1 | Methods for the identification of PI3K interacting molecules and for the purification of PI3K | CELLZOME AG (DE) | 2008-11-12 | — | — | EP | disclosed |
| EP-1887359-B1 | Methods for the identification of PI3K interacting molecules and for the purification of PI3K | CELLZOME AG (DE) | 2008-11-12 | — | — | EP | disclosed |
| EP-1887359-A1 | Methods for the identification of PI3K interacting molecules and for the purification of PI3K | CELLZOME AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| EP-1887359-A1 | Methods for the identification of PI3K interacting molecules and for the purification of PI3K | CELLZOME AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| WO-2008015013-A1 | METHODS FOR THE IDENTIFICATION OF PI3K INTERACTING MOLECULES AND FOR THE PURIFICATION OF PI3K | CELLZOME AG (DE) | 2008-02-07 | — | — | WO | disclosed |