Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | CCR8 | P51685 | 2/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL434860 | 0.84 | CYP1A2 (0.57) | CYP1A2PDGFRBPDGFRACCR1CCR5 | |
| SCHEMBL7157574 | 0.81 | PDGFRB (0.59) | CYP1A2PDGFRBPDGFRANR4A2HRH4 | |
| SCHEMBL30702581 | 0.81 | PDGFRB (0.59) | CYP1A2PDGFRBPDGFRANR4A2HRH4 | |
| SCHEMBL7747338 | 0.81 | CYP1A2 (0.63) | CYP1A2CCR1CCR5CCR8KMT2A | |
| SCHEMBL13356513 | 0.76 | PDGFRB (0.54) | CYP1A2PDGFRBPDGFRANR4A2POLB | |
| SCHEMBL5534628 | 0.76 | CYP1A2 (0.57) | CYP1A2CCR1CCR5CCR8KMT2A | |
| SCHEMBL8268977 | 0.76 | ALDH1A1 (0.50) | CYP1A2PDGFRBPDGFRAKMT2AKDM4E | |
| SCHEMBL5534632 | 0.76 | ESR2 (0.59) | CYP1A2PDGFRBPDGFRACCR1CCR5 | |
| SCHEMBL12991057 | 0.76 | CYP1A2 (0.57) | CYP1A2PDGFRBPDGFRACCR1CCR5 | |
| SCHEMBL16070947 | 0.76 | CYP1A2 (0.57) | CYP1A2CCR1CCR5CCR8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472587-B1 | PRODUCTION OF A 5-(2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY)-2-NITROBENZOIC ACID OR 7-CHLORO-3-METHYLLQUINOLINE-8-CARBOXYLIC ACID-TOLERANT PLANT BY EXPRESSING AN EXOGENOUS 5-(2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY)-2-NITROBENZOIC ACID OR 7-CHLORO-3-METHYLLQUINOLINE-8-CARBOXYLIC ACID-BINDING ANTIBODY IN THE PLANT | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |
| US-4124386-A | Color diffusion transfer receiving layer comprising polymeric quaternary n-heterocyclic mordant | FUJI PHOTO FILM CO., LTD. (JP) | 1978-11-07 | — | — | US | claimed |
| WO-2024108147-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-3752201-B1 | SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF | UNIV FRIEDRICH ALEXANDER ER (DE) | 2023-11-22 | — | — | EP | disclosed |
| CN-111936667-B | Method for producing laminate | 大金工业株式会社 | 2022-12-13 | — | — | CN | disclosed |
| WO-2021113698-A1 | MASP-2 INHIBITORS AND METHODS OF USE | OMEROS CORPORATION (US) | 2021-06-10 | — | — | WO | disclosed |
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-05-07 | — | — | US | disclosed |
| US-9975891-B2 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-22 | — | — | US | disclosed |
| US-9975891-B2 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-05-22 | — | — | US | disclosed |
| US-9655363-B2 | Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-23 | — | — | US | disclosed |
| US-9655363-B2 | Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-23 | — | — | US | disclosed |
| US-20030181496-A1 | Pyrrole derivatives | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| WO-2003047520-A2 | SUBSTITUTED AMINO METHYL FACTOR Xa INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |
| WO-2003048081-A2 | GLYCINAMIDES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |
| EP-1310485-A1 | PYRROLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2003-05-14 | — | — | EP | disclosed |
| WO-2003026652-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |
| EP-0294685-A2 | Process for the preparation of quinolines | BASF Aktiengesellschaft (DE) | 1988-12-14 | — | — | EP | disclosed |
| US-4124386-A | Color diffusion transfer receiving layer comprising polymeric quaternary n-heterocyclic mordant | FUJI PHOTO FILM CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |
| US-4021428-A | 4-Piperidino-5-oxo-2-pyrazolines | FUJI PHOTO FILM CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |
| US-3956339-A | 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use | FUJI PHOTO FILM CO., LTD. (JA) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181496-A1 | Pyrrole derivatives | NCOA1, PKD1, NR3C2 | CYP1A2 273/4885PDGFRB 131/4885PDGFRA 156/4885 |
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | F12, F2, CPB1 | CYP1A2 1188/4885PDGFRB 2382/4885PDGFRA 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.