⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Boric Acid SCHEMBL27507345 | 0.90 | CES2 (0.41) | — | |
| Boric Acid SCHEMBL28194678 | 0.90 | CES2 (0.41) | — | |
| SCHEMBL2158778 | 0.77 | — | — | |
| SCHEMBL13329 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL28687887 | 0.74 | ACHE (0.46) | — | |
| SCHEMBL29045690 | 0.74 | — | — | |
| SCHEMBL30097987 | 0.74 | — | — | |
| SCHEMBL28445505 | 0.74 | ACHE (0.58) | — | |
| Hydrochloric Acid SCHEMBL1701450 | 0.74 | — | — | |
| SCHEMBL30577824 | 0.74 | ACHE (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727648-A1 | CANNABINOID RECEPTOR 2 MODULATORS | F. Hoffmann-La Roche AG (CH) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256505-A1 | CANNABINOID RECEPTOR 2 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-12-19 | — | — | WO | disclosed |
| CN-106574008-A | Polycyclo-olefinic block polymers and pervaporation membranes made therefrom | 普罗米鲁斯有限责任公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-1972938-B | Cyclic amine compound | TAISHO PHARMACEUTICAL CO LTD | 2010-09-29 | — | — | CN | disclosed |
| US-7615634-B2 | 4-aminopyrimidine-5-one derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-11-10 | — | — | US | disclosed |
| US-7601734-B2 | Such as methyl 5-(3,4-dihydro[1]benzofuro[3,2-c]pyridine-2(1H)-yl)-2,2-bis(4-fluorophenyl)pentanoate, having potent inhibitory effect on binding of alpha 2C-adrenoceptor; depression, anxiety, schizophrenia | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20070244145-A1 | Cyclic Amine Compound | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2007-10-18 | — | — | US | disclosed |
| CN-1972938-A | Cyclic amine compound | TAISHO PHARMACEUTICAL CO LTD (JP) | 2007-05-30 | — | — | CN | disclosed |
| EP-1757605-A1 | CYCLIC AMINE COMPOUND | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-7157455-B2 | 4-Aminopyrimidine-5-one derivatives | HOFFMANN-LA ROCHE INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060229330-A1 | 4-aminopyrimidine-5-one derivatives | BARTKOVITZ DAVID J | 2006-10-12 | — | — | US | disclosed |
| EP-1628619-A2 | 4-AMINOPYRIMIDINE-5-ONE | F.HOFFMANN-LA ROCHE AG (CH) | 2006-03-01 | — | — | EP | disclosed |
| US-20040162303-A1 | 4-aminopyrimidine-5-one derivatives | BARTKOVITZ DAVID JOSEPH (US) | 2004-08-19 | — | — | US | disclosed |
| WO-2004069139-A2 | 4-AMINOPYRIMIDIN-5-YL-METHANONE DERIVATIVES FOR INHIBITION OF CDK4 ACTIVITY | F.HOFFMANN-LA ROCHE AG (CH) | 2004-08-19 | — | — | WO | disclosed |