Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A5 | P05141 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | HBB | P68871 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15976145 | 0.78 | SLC25A5 (0.64) | SLC25A5MAPTHTTALOX15HBB | |
| SCHEMBL11451081 | 0.75 | MAPT (1.00) | SLC25A5MAPTHTTALOX15HBB | |
| Dibenzoylmethane SCHEMBL39582 | 0.73 | MEN1 (1.00) | SLC25A5MAPTHTTALOX15MEN1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.73 | MEN1 (1.00) | SLC25A5MAPTHTTALOX15MEN1 | |
| Dibenzoylmethane SCHEMBL10356288 | 0.73 | MEN1 (1.00) | SLC25A5MAPTHTTALOX15MEN1 | |
| SCHEMBL8893921 | 0.72 | MAPT (0.65) | SLC25A5MAPTHTTALOX15HBB | |
| SCHEMBL9722483 | 0.72 | MEN1 (0.61) | SLC25A5MAPTHTTALOX15MEN1 | |
| SCHEMBL4251157 | 0.72 | MEN1 (0.61) | SLC25A5MAPTHTTALOX15MEN1 | |
| Dibenzoylmethane SCHEMBL6249492 | 0.71 | MEN1 (0.94) | SLC25A5MAPTHTTALOX15MEN1 | |
| Dibenzoylmethane SCHEMBL531257 | 0.71 | MEN1 (0.94) | SLC25A5MAPTHTTALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009126335-A2 | ANT2 INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-10-15 | — | — | WO | disclosed |