Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC25A5 | P05141 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HBB | P68871 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 13/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 7/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646251 | 0.81 | ALDH1A1 (0.49) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL4357878 | 0.78 | SLC25A5 (1.00) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL2112664 | 0.77 | HBB (0.61) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL353367 | 0.76 | SLC25A5 (1.00) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL29354821 | 0.76 | SLC25A5 (1.00) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL10896508 | 0.74 | SLC25A5 (0.96) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| Calcium SCHEMBL29827230 | 0.74 | SLC25A5 (0.96) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL9512613 | 0.74 | SLC25A5 (0.57) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL22802235 | 0.72 | SLC25A5 (0.54) | SLC25A5ALDH1A1HBBHSD17B10MAPT | |
| SCHEMBL8893921 | 0.70 | MAPT (0.65) | SLC25A5ALDH1A1HBBHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815828-B2 | Therapeutic combinations for use in neoplasia | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-08-26 | — | — | US | disclosed |