SCHEMBL435809

SCHEMBL435809

O=S(=O)(Oc1ccc(Cl)cc1Cl)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
ALDH1A1 P00352 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAA P10253 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KMT2A Q03164 3/20 0.45
FLT1 P17948 1/20 0.44
FLT4 P35916 1/20 0.44
KDR P35968 1/20 0.44
MAPT P10636 5/20 0.43
CHRM1 P11229 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
RAB9A P51151 2/20 0.43
ENPP3 O14638 1/20 0.43
ENPP1 P22413 1/20 0.43
LMNA P02545 1/20 0.43
MRGPRX4 Q96LA9 2/20 0.42
PPARA Q07869 1/20 0.42
METAP2 P50579 1/20 0.42
METAP1 P53582 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350285 1.00 TDP1 (0.59) TDP1ALDH1A1SMN1; SMN2GAANPSR1
SCHEMBL10577996 0.83 KMT2A (0.63) ALDH1A1GAAKMT2AFLT1FLT4
SCHEMBL8330761 0.83 KMT2A (0.49) TDP1ALDH1A1SMN1; SMN2GAAKMT2A
SCHEMBL31425689 0.83 TDP1 (0.47) TDP1SMN1; SMN2GAANPSR1KMT2A
SCHEMBL9056306 0.82 ALDH1A1 (0.58) TDP1ALDH1A1SMN1; SMN2GAANPSR1
SCHEMBL11507793 0.79 MAPT (0.48) TDP1ALDH1A1GAAKMT2AMAPT
SCHEMBL9751922 0.79 SMN1; SMN2 (0.47) TDP1SMN1; SMN2GAANPSR1KMT2A
SCHEMBL11586321 0.77 TSHR (0.50) TDP1ALDH1A1SMN1; SMN2GAAKMT2A
SCHEMBL11500270 0.75 HIF1A (0.53) TDP1ALDH1A1SMN1; SMN2GAANPSR1
SCHEMBL31272384 0.75 ALDH1A1 (0.68) TDP1ALDH1A1SMN1; SMN2KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1886 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2026-05-21 US claimed
EP-4627920-A1 BINARY INSECTICIDE COMPOSITION AND USE THEREOF Shenyang Sinochem Agrochemicals R & D Co., Ltd. (CN) 2025-10-08 EP claimed
US-20250017207-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-01-16 US claimed
EP-4422404-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
EP-4422402-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL Syngenta Crop Protection AG (CH) 2024-09-04 EP claimed
WO-2024114260-A1 BINARY INSECTICIDE COMPOSITION AND USE THEREOF 沈阳中化农药化工研发有限公司 2024-06-06 WO claimed
CN-118104669-A Synergistic compound composition of two active components and application thereof 沈阳中化农药化工研发有限公司 2024-05-31 CN claimed
CN-118019451-A Fungicidal compositions comprising fludioxonil 先正达农作物保护股份公司 2024-05-10 CN claimed
WO-2023072785-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
WO-2023072784-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL SYNGENTA CROP PROTECTION AG (CH) 2023-05-04 WO claimed
EP-1802198-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-07-04 EP claimed
EP-1796464-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-06-20 EP claimed
EP-1778013-A1 FUNGICIDAL COMPOSITIONS Syngeta Participations AG (CH) 2007-05-02 EP claimed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 WO claimed
WO-2006037632-A1 SYNERGISTIC FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO claimed
WO-2006037633-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO claimed
WO-2006037634-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-04-13 WO claimed
WO-2006015865-A1 FUNGICIDAL COMPOSITIONS SYNGENTA PARTICIPATIONS AG (CH) 2006-02-16 WO claimed
US-20020160107-A1 Asphalt paving method including liquid sealer AMON THOMAS R (US) 2002-10-31 US claimed
EP-0230478-A1 Method for producing alpha-(p-isobutylphenyl)propionic acid NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1987-08-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250017207-A1 FUNGICIDAL COMPOSITIONS CYP51A1, BROX, DPM1 TDP1 903/4885ALDH1A1 1605/4885SMN1; SMN2 4238/4885
US-20260137082-A1 FUNGICIDAL COMPOSITIONS COMPRISING FLUDIOXONIL NOTUM, CTRL, BROX TDP1 793/4885ALDH1A1 2077/4885SMN1; SMN2 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.