Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 6/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 5/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 3/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.37 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263391 | 0.87 | GAA (0.49) | GAASLC2A1SLC2A3SLC2A2SLC2A4 | |
| SCHEMBL4359090 | 0.78 | KMT2A (0.40) | GAASLC2A1SLC2A3SLC2A2SLC2A4 | |
| SCHEMBL4357027 | 0.77 | TACR3 (0.46) | SLC2A1ALDH1A1TACR3ADORA2AADORA1 | |
| SCHEMBL8264900 | 0.77 | SMN1; SMN2 (0.53) | GAATACR3KDM4E | |
| SCHEMBL4361680 | 0.77 | TACR3 (0.45) | SLC2A1ALDH1A1TACR3ADORA2AADORA1 | |
| SCHEMBL4358870 | 0.74 | TACR3 (0.43) | SLC2A1TACR3ADORA2AADORA1 | |
| SCHEMBL13619216 | 0.74 | TACR3 (0.44) | SLC2A1SLC6A9TACR3ADORA2AADORA1 | |
| SCHEMBL4351001 | 0.73 | TACR3 (0.38) | GAASLC2A1SLC6A9TACR3 | |
| SCHEMBL13303748 | 0.73 | SLC6A9 (0.48) | SLC6A9 | |
| SCHEMBL4363718 | 0.73 | TACR3 (0.43) | SLC2A1TACR3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286828-A1 | 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286828-A1 | 2-AMINO-1-PHENYLETHYLCARBOXAMIDE DERIVATIVES | PNMT, SLC18A2, COMT | GAA 110/4885SLC2A1 1844/4885SLC2A3 2239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.