Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E968 SCHEMBL29367165 | 0.92 | ALDH1A1 (0.41) | GLRA3GLRBVCAM1GPR55CYP1A2 | |
| SCHEMBL100584 | 0.90 | GLRA3 (0.50) | GLRA3GLRBGPR55CYP1A2CA2 | |
| SCHEMBL6275312 | 0.90 | GLRA3 (0.50) | GLRA3GLRBGPR55CYP1A2CA2 | |
| Hydrogen Sulfide SCHEMBL27550937 | 0.89 | GLRA3 (0.48) | GLRA3GLRBGPR55CYP1A2CA2 | |
| Methane SCHEMBL4556718 | 0.89 | GLRA3 (0.48) | GLRA3GLRBGPR55CYP1A2CA2 | |
| SCHEMBL27309992 | 0.89 | GLRA3 (0.48) | GLRA3GLRBGPR55CYP1A2CA2 | |
| Hydrochloric Acid SCHEMBL1874072 | 0.89 | GLRA3 (0.48) | GLRA3GLRBGPR55CYP1A2CA2 | |
| SCHEMBL38652274 | 0.89 | GLRA3 (0.48) | GLRA3GLRBGPR55CYP1A2CA2 | |
| Charcoal, Activated SCHEMBL30758836 | 0.89 | GLRA3 (0.48) | GLRA3GLRBGPR55CYP1A2CA2 | |
| SCHEMBL1650114 | 0.88 | ALDH1A1 (0.42) | GLRA3GLRBVCAM1GPR55CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090251643-A1 | POLARIZING PLATE, MANUFACTURING METHOD OF POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY APPARATUS | KONICA MINOLTA OPTO, INC. (JP) | 2009-10-08 | — | — | US | disclosed |