Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | PNLIP | P16233 | 2/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2185238 | 0.85 | TRPA1 (0.41) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL11447720 | 0.81 | PTPN1 (0.38) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL11455730 | 0.81 | PTPN1 (0.38) | TRPA1PTPN1PTPN2PNLIPCYP3A4 | |
| SCHEMBL11316490 | 0.81 | TRPA1 (0.36) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL11447719 | 0.81 | PTPN1 (0.38) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL11447721 | 0.81 | PTPN1 (0.38) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL23530425 | 0.80 | TRPA1 (0.39) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL755859 | 0.80 | TRPA1 (0.39) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL17129801 | 0.80 | TRPA1 (0.38) | TRPA1PTPN1PTPN2NR3C1PGR | |
| SCHEMBL29414123 | 0.80 | TRPA1 (0.39) | TRPA1PTPN1PTPN2NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4268806-B2 | — | — | 2009-05-27 | — | — | JP | claimed |
| EP-1395542-B1 | CATALYTIC SYSTEM FOR ALDOL REACTIONS | FIRMENICH & CIE (CH) | 2006-08-16 | — | — | EP | claimed |
| US-6838575-B2 | Catalytic system for aldol reactions | FIRMENICH SA (CH) | 2005-01-04 | — | — | US | claimed |
| JP-2004529190-A | — | — | 2004-09-24 | — | — | JP | claimed |
| US-20040082818-A1 | Catalytic system for aldol reactions | FIRMENICH SA (CH) | 2004-04-29 | — | — | US | claimed |
| EP-1395542-A1 | CATALYTIC SYSTEM FOR ALDOL REACTIONS | FIRMENICH SA (CH) | 2004-03-10 | — | — | EP | claimed |
| WO-2002094755-A1 | CATALYTIC SYSTEM FOR ALDOL REACTIONS | FIRMENICH SA (CH) | 2002-11-28 | — | — | WO | claimed |
| EP-1697290-B1 | PROCESS FOR THE ISOMERISATION OF A CYCLOHEXENYL ALKYL OR ALKENYL KETONE | FIRMENICH & CIE (CH) | 2012-09-12 | — | — | EP | disclosed |
| US-7250536-B2 | Process for the isomerisation of a cyclohexenyl alkyl or alkenyl ketone | FIRMENICH SA (CH) | 2007-07-31 | — | — | US | disclosed |
| US-20060211889-A1 | Process for the isomerisation of a cyclohexenyl alkyl or alkenyl ketone | FIRMENICH SA (CH) | 2006-09-21 | — | — | US | disclosed |
| EP-1697290-A1 | PROCESS FOR THE ISOMERISATION OF A CYCLOHEXENYL ALKYL OR ALKENYL KETONE | FIRMENICH SA (CH) | 2006-09-06 | — | — | EP | disclosed |
| EP-1395542-B1 | CATALYTIC SYSTEM FOR ALDOL REACTIONS | FIRMENICH & CIE (CH) | 2006-08-16 | — | — | EP | disclosed |
| US-7091151-B2 | Catalytic system for aldol reactions | FIRMENICH SA (CH) | 2006-08-15 | — | — | US | disclosed |
| WO-2005061426-A1 | PROCESS FOR THE ISOMERISATION OF A CYCLOHEXENYL ALKYL OR ALKENYL KETONE | FIRMENICH SA (CH) | 2005-07-07 | — | — | WO | disclosed |
| US-20050080297-A1 | Group IV metal alkoxy halide complex and an alkyl or aryl carboxylic anhydride, BF3 or an anhydrous sulfate, chloride or bromide of Li+, Na+, K+, Cs+, Mg2+, Ni2+, Ca2+, Zn2+, Fe3+ or Al3+; for the one step aldol condensation of a ketone, e.g., a gem-dimethyl cyclohexylethanone with an aldehyde | FIRMENICH SA (CH) | 2005-04-14 | — | — | US | disclosed |
| US-6838575-B2 | Catalytic system for aldol reactions | FIRMENICH SA (CH) | 2005-01-04 | — | — | US | disclosed |
| US-20040082818-A1 | Catalytic system for aldol reactions | FIRMENICH SA (CH) | 2004-04-29 | — | — | US | disclosed |
| EP-1395542-A1 | CATALYTIC SYSTEM FOR ALDOL REACTIONS | FIRMENICH SA (CH) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094755-A1 | CATALYTIC SYSTEM FOR ALDOL REACTIONS | FIRMENICH SA (CH) | 2002-11-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080297-A1 | Group IV metal alkoxy halide complex and an alkyl or aryl carboxylic anhydride, BF3 or an anhydrous sulfate, chloride or bromide of Li+, Na+, K+, Cs+, Mg2+, Ni2+, Ca2+, Zn2+, Fe3+ or Al3+; for the one step aldol condensation of a ketone, e.g., a gem-dimethyl cyclohexylethanone with an aldehyde | AKR1C3, CBR3, AKR1C2 | TRPA1 899/4885PTPN1 4770/4885PTPN2 4722/4885 |
| US-20060211889-A1 | Process for the isomerisation of a cyclohexenyl alkyl or alkenyl ketone | AKR1C3, AKR7A2, AKR1C2 | TRPA1 2171/4885PTPN1 4664/4885PTPN2 4398/4885 |
| US-20040082818-A1 | Catalytic system for aldol reactions | AKR1B10, AGL, AKR1C2 | TRPA1 2394/4885PTPN1 4797/4885PTPN2 4766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.