Succinyl-Coa

Succinyl-Coa

SCHEMBL4360968

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)C(O)C(=O)NCCC(=O)NCCSC(=O)CCC(=O)O

nearest known ligand 0.93

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Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.87
▸ CHAT P28329 2/20 0.83
▸ EP300 Q09472 3/20 0.82
▸ KAT5 Q92993 2/20 0.82
▸ AURKA O14965 2/20 0.82
▸ KAT2B Q92831 1/20 0.82
▸ CREBBP Q92793 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinyl-Coa SCHEMBL4364428 1.00 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL28138807 1.00 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL31385487 1.00 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL30927108 1.00 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL50744 1.00 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL4360979 1.00 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL28059593 1.00 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL1643484 0.99 NAA50 (0.86) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL31108060 0.99 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL5529148 0.98 NAA50 (0.84) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119193522-A 5-Aminolevulinic acid synthetase mutant and application thereof 中国农业科学院植物保护研究所 2024-12-27 — — CN claimed
CN-118792383-A OXCT1 protein ketone body decomposition enzyme activity detection method 合肥综合性国家科学中心大健康研究院 2024-10-18 — — CN claimed
CN-118726296-A Method for modifying aspartate aminotransferase in honeysuckle by in-vitro succinylation and application 浙江理工大学 2024-10-01 — — CN claimed
CN-118546964-A Coli engineering bacteria for high yield of 5-aminolevulinic acid, construction method and application thereof 中国科学院微生物研究所 2024-08-27 — — CN claimed
CN-118526587-A Application of targeted Succinyl-CoA in treatment of rheumatoid arthritis 苏州大学 2024-08-23 — — CN claimed
CN-118345105-A Method for producing L-theanine gene engineering bacteria 汝州市坤和生物科技有限公司 2024-07-16 — — CN claimed
CN-118255841-A OXCT1 succinyl transferase inhibitor screening method based on fluorescence polarization technology 合肥综合性国家科学中心大健康研究院 2024-06-28 — — CN claimed
CN-115747125-B Engineering strain for high yield of 5-aminolevulinic acid and construction method of high yield strain of 5-aminolevulinic acid 中国科学院天津工业生物技术研究所 2024-06-14 — — CN claimed
CN-111386339-B Genetically modified microorganisms for producing 3-hydroxy adipic acid, alpha-hydrogenated hexadienoic acid and/or adipic acid and method for producing the chemical products 东丽株式会社 2024-05-10 — — CN claimed
CN-116801892-A Adipogenic cell compositions and methods 旗舰创业股份有限公司 2023-09-22 — — CN claimed
CN-113699090-B Method for constructing propionic acid producing bacteria 浙江华睿生物技术有限公司 2023-06-20 — — CN claimed
CN-109154008-B Process for producing 3-hydroxyadipic acid 东丽株式会社 2022-05-31 — — CN claimed
CN-114341344-A Engineered microorganisms and methods for improving aldehyde dehydrogenase activity 基因组股份公司 2022-04-12 — — CN claimed
CN-114144513-A Fermentative production of beta-ketoadipate from gaseous substrates 朗泽科技有限公司 2022-03-04 — — CN claimed
CN-109370965-B Genetically engineered bacterium for synthesizing 1, 3-propanediol from glucose and application thereof 北京化工大学 2021-11-26 — — CN claimed
CN-107459545-B Method for extracting intracellular coenzyme A and organic acid of saccharopolyspora erythraea 华东理工大学 2020-09-08 — — CN claimed
CN-106350474-A Mutant Microorganism Comprising Gene Encoding Methylmalonyl-CoA Reductase and Use Thereof SK新技术株式会社 2017-01-25 — — CN claimed
CN-122005601-A Use of vitamin B12 天津医科大学 2026-05-12 — — CN disclosed
CN-101151011-A Oral care regimens and devices PROCTER & GAMBLE (US) 2008-03-26 — — CN disclosed
CN-1367841-A Methods and materials for synthesis of organic products CARGILLDOU CO LTD (US) 2002-09-04 — — CN disclosed
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