Sugi Predict

Sugi Predict / Compounds / Succinyl-Coa

Succinyl-Coa

Succinyl-Coa

SCHEMBL5529148

CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CCC(=O)O.NCC(=O)O

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D

The experimentally established mechanism targets of Succinyl-Coa. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NAA50 Q9GZZ1 2/20 0.84
▸ CHAT P28329 2/20 0.81
▸ EP300 Q09472 3/20 0.79
▸ KAT5 Q92993 2/20 0.79
▸ AURKA O14965 2/20 0.79
▸ KAT2B Q92831 1/20 0.79
▸ CREBBP Q92793 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinyl-Coa SCHEMBL31385487 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL28138807 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL30927108 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL50744 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL28059593 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL4360968 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL4360979 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL4364428 0.98 NAA50 (0.87) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL1643484 0.98 NAA50 (0.86) NAA50CHATEP300KAT5AURKA
Succinyl-Coa SCHEMBL31108060 0.97 NAA50 (0.87) NAA50CHATEP300KAT5AURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7261887-B2 Leishmania as carriers for the delivery of proteins and peptides ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE (US) 2007-08-28 — — US disclosed
US-7238347-B2 Suicidal mutant Leishmania vaccine ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE (US) 2007-07-03 — — US disclosed
US-20060018888-A1 Suicidal mutant leishmania vaccine ROSALIND FRANKLIN UNIVERSITY OF MEDICINE & SCIENCE 2006-01-26 — — US disclosed
US-20040092467-A1 Biological carriers for the delivery of proteins or peptides ROSALIND FRANKLIN UNIVERSITY OF MEDICINE & SCIENCE 2004-05-13 — — US disclosed
Send feedback