Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.53 |
| ▸ | ADK | P55263 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983476 | 0.86 | PIK3CG (0.71) | PIK3CGADKALDH1A1KDM4EHTT | |
| SCHEMBL1351376 | 0.82 | AKT1 (0.51) | — | |
| SCHEMBL14983464 | 0.81 | PIK3CG (0.65) | PIK3CGADKALDH1A1KDM4EHTT | |
| Hydrochloric Acid SCHEMBL1351917 | 0.81 | AKT1 (0.50) | — | |
| Hydrochloric Acid SCHEMBL1351112 | 0.81 | AKT1 (0.50) | — | |
| SCHEMBL14983475 | 0.79 | PIK3CG (0.50) | PIK3CGADKALDH1A1KDM4EHPGD | |
| SCHEMBL3742316 | 0.79 | ADK (0.76) | PIK3CGADKALDH1A1KDM4EHTT | |
| SCHEMBL17089216 | 0.78 | PIK3CG (0.55) | PIK3CGALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL3533590 | 0.76 | PIK3CG (0.50) | PIK3CGADKALDH1A1KDM4EHTT | |
| SCHEMBL3252241 | 0.76 | PIK3CG (0.48) | PIK3CGADKNOS1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039683-B1 | Vasculostatic agents and methods of use thereof | TARGEGEN INC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2039683-A2 | Vasculostatic agents and methods of use thereof | Targegen, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |