Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 4/20 | 0.48 |
| ▸ | ADK | P55263 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL11470117 | 0.94 | PIK3CG (0.44) | PIK3CGADKNOS1NPC1PDGFRB | |
| SCHEMBL11472836 | 0.84 | PIK3CG (0.47) | PIK3CGADKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11470380 | 0.84 | ADK (0.56) | PIK3CGADKNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11478905 | 0.82 | PIK3CG (0.48) | PIK3CGADK | |
| SCHEMBL11467366 | 0.82 | BCHE (0.53) | PIK3CGADKBCHE | |
| SCHEMBL11470116 | 0.80 | ADK (0.71) | PIK3CGADKNOS1 | |
| SCHEMBL11446163 | 0.80 | ADK (0.67) | PIK3CGADKNOS1 | |
| SCHEMBL11467784 | 0.76 | ALDH1A1 (0.47) | ADKNOS1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4361291 | 0.76 | PIK3CG (0.53) | PIK3CGADKNOS1SMN1; SMN2 | |
| SCHEMBL13019092 | 0.72 | CSF1R (0.54) | ADKRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511852-B1 | USE OF FLUORINE NMR FOR HIGH THROUGHPUT SCREENING | NERVIANO MEDICAL SCIENCES SRL (IT) | 2010-05-26 | — | — | EP | disclosed |
| US-7470543-B2 | Methods for identifying ligands using competitive binding 1H NMR experiments | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2008-12-30 | — | — | US | disclosed |
| EP-1511852-A4 | USE OF FLUORINE NMR FOR HIGH THROUGHPUT SCREENING | PHARMACIA & UPJOHN CO LLC (US) | 2008-07-16 | — | — | EP | disclosed |
| CN-1668757-A | Use of fluorine nmr for high throughput screening | UPJOHN CO (US) | 2005-09-14 | — | — | CN | disclosed |
| EP-1511988-A4 | METHODS FOR IDENTIFYING LIGANDS USING COMPETITIVE BINDING sp 1 /sp H NMR EXPERIMENTS | PHARMACIA & UPJOHN CO LLC (US) | 2005-07-06 | — | — | EP | disclosed |
| EP-1511988-A1 | METHODS FOR IDENTIFYING LIGANDS USING COMPETITIVE BINDING sp 1 /sp H NMR EXPERIMENTS | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-09 | — | — | EP | disclosed |
| EP-1511852-A2 | USE OF FLUORINE NMR FOR HIGH THROUGHPUT SCREENING | PHARMACIA & UPJOHN COMPANY (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2004051214-A2 | USE OF FLUORINE NMR FOR HIGH THROUGHPUT SCREENING | PHARMACIA & UPJOHN COMPANY (US) | 2004-06-17 | — | — | WO | disclosed |
| US-20040091937-A1 | Use of fluorine NMR for high throughput screening | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2004-05-13 | — | — | US | disclosed |
| US-20040072362-A1 | Methods for identifying ligands using competitive binding 1H NMR experiments | PHARMACIA & UPJOHN COMPANY | 2004-04-15 | — | — | US | disclosed |
| WO-2003104778-A1 | METHODS FOR IDENTIFYING LIGANDS USING COMPETITIVE BINDING 1H NMR EXPERIMENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |
| US-4183934-A | NONALIURETIC DIURETICS | ABBOTT LABORATORIES (US) | 1980-01-15 | — | — | US | disclosed |