⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888371 | 0.73 | — | — | |
| SCHEMBL4213265 | 0.71 | MMP1 (0.32) | — | |
| SCHEMBL4207907 | 0.71 | — | — | |
| SCHEMBL11338524 | 0.71 | — | — | |
| SCHEMBL888520 | 0.69 | — | — | |
| SCHEMBL4207802 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL4207783 | 0.67 | KDM4E (0.30) | — | |
| SCHEMBL4201698 | 0.65 | — | — | |
| SCHEMBL4204942 | 0.65 | THRB (0.30) | — | |
| SCHEMBL723995 | 0.65 | TDP1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618949-B2 | Drug-eluting stents coated with P2Y12 receptor antagonist compound | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-20090253873-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME | TOHO CATALYST CO., LTD (JP) | 2009-10-08 | — | — | US | disclosed |
| US-20080287671-A1 | DRUG-ELUTING STENTS COATED WITH P2Y12 RECEPTOR ANTAGONIST COMPOUND | BOYER JOSE L | 2008-11-20 | — | — | US | disclosed |
| US-7452870-B2 | Drug-eluting stents coated with P2Y12 receptor antagonist compound | INSPIRE PHARMACEUTICALS, INC. (US) | 2008-11-18 | — | — | US | disclosed |
| EP-1829898-A1 | SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME | Toho Catalyst Co., Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |
| EP-1758915-A2 | COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | Inspire Pharmaceuticals, Inc. (US) | 2007-03-07 | — | — | EP | disclosed |
| US-7132408-B2 | Composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2006-11-07 | — | — | US | disclosed |
| US-7101860-B2 | Composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. (US) | 2006-09-05 | — | — | US | disclosed |
| US-20060122143-A1 | Drug-eluting stents coated with P2Y12 receptor antagonist compound | INSPIRE PHARMACEUTICALS, INC. | 2006-06-08 | — | — | US | disclosed |
| WO-2005097814-A2 | COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| US-20040220133-A1 | Composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. | 2004-11-04 | — | — | US | disclosed |
| EP-1311525-A2 | COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | Inspire Pharmaceuticals, Inc. (US) | 2003-05-21 | — | — | EP | disclosed |
| US-20020052337-A1 | Composition and method for inhibiting platelet aggregation | NORTH CAROLINA, UNIVERSITY OF | 2002-05-02 | — | — | US | disclosed |
| WO-2002016381-A2 | COMPOSITION AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS, INC. (US) | 2002-02-28 | — | — | WO | disclosed |