SCHEMBL436200

SCHEMBL436200

CC(C)=CC1C(C)(C)C1(Cc1c(F)c(F)cc(F)c1F)C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7918126 1.00 CA1 (0.30) CA1CA2CA4
SCHEMBL585683 0.89 CA1 (0.30) CA1CA2CA4
SCHEMBL3400248 0.89 CA1 (0.30) CA1CA2CA4
SCHEMBL4610974 0.89 CA1 (0.30) CA1CA2CA4
SCHEMBL16411945 0.89 CA1 (0.30) CA1CA2CA4
SCHEMBL8097718 0.87
SCHEMBL2058801 0.85 MEN1 (0.34)
SCHEMBL439569 0.85 MEN1 (0.34)
SCHEMBL439286 0.84
SCHEMBL7918020 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7459168-B2 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2008-12-02 US claimed
EP-1352562-B1 Insecticide transpiration apparatus DAINIPPON JOCHUGIKU KK (JP) 2006-11-15 EP claimed
US-6926902-B2 Insecticide transpiration apparatus DAINHON JOCHUGIKU CO., LTD. (JP) 2005-08-09 US claimed
US-20040180070-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2004-09-16 US claimed
EP-1352562-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-10-15 EP claimed
US-20030160062-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-08-28 US claimed
US-9238078-B2 Modified-release pharmaceutical drug composition COATING PLACE, INC. (US) 2016-01-19 US disclosed
US-9125948-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2015-09-08 US disclosed
US-8883213-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2014-11-11 US disclosed
US-8343546-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2013-01-01 US disclosed
US-8329224-B2 Ion exchange resin treated to control swelling COATING PLACE, INC. (US) 2012-12-11 US disclosed
US-20120064167-A1 MODIFIED-RELEASE PHARMACEUTICAL DRUG COMPOSITION COATING PLACE, INC. (US) 2012-03-15 US disclosed
EP-2413898-A1 MODIFIED-RELEASE PHARMACEUTICAL DRUG COMPOSITION Coating Place, Inc. (US) 2012-02-08 EP disclosed
WO-2007033281-A2 ION EXCHANGE RESIN TREATED TO CONTROL SWELLING COATING PLACE, INC. (US) 2007-03-22 WO disclosed
US-20070059270-A1 Loading one or more drugs in a solution onto one or more ion exchange resin particles to form a drug-loaded resin particle which is separated from the solution and dried before recombining the drug-loaded resin particle with the solution to load more drugs onto the drug-load; controlled release THE COATING PLACE, INC. (US) 2007-03-15 US disclosed
EP-1352562-B1 Insecticide transpiration apparatus DAINIPPON JOCHUGIKU KK (JP) 2006-11-15 EP disclosed
US-6926902-B2 Insecticide transpiration apparatus DAINHON JOCHUGIKU CO., LTD. (JP) 2005-08-09 US disclosed
US-20040180070-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2004-09-16 US disclosed
EP-1352562-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-10-15 EP disclosed
US-20030160062-A1 Insecticide transpiration apparatus DAINIHON JOCHUGIKU CO., LTD. (JP) 2003-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180070-A1 Insecticide transpiration apparatus TIMM13, PIK3C3, ATP5PD CA1 1450/4885CA2 2856/4885CA4 3468/4885
US-20030160062-A1 Insecticide transpiration apparatus PIK3C3, ACHE, ATP5PD CA1 1760/4885CA2 3211/4885CA4 4089/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.