Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4366640 | 0.94 | SLC8A1 (0.49) | SLC8A1HRH3 | |
| SCHEMBL4358510 | 0.92 | SLC8A1 (0.52) | SLC8A1HRH3 | |
| SCHEMBL4358815 | 0.92 | SLC8A1 (0.47) | SLC8A1HRH3 | |
| SCHEMBL4366455 | 0.92 | SLC8A1 (0.45) | SLC8A1HRH3 | |
| SCHEMBL4954306 | 0.91 | HRH3 (0.51) | SLC8A1HRH3 | |
| SCHEMBL4362276 | 0.91 | SLC8A1 (0.46) | SLC8A1HRH3 | |
| SCHEMBL4364010 | 0.90 | SLC8A1 (0.46) | SLC8A1 | |
| SCHEMBL4358398 | 0.89 | SLC8A1 (0.55) | SLC8A1 | |
| SCHEMBL4368895 | 0.89 | SLC8A1 (0.48) | SLC8A1 | |
| SCHEMBL4368031 | 0.88 | SLC8A1 (0.47) | SLC8A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482340-B2 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system | ORION CORPORATION (FI) | 2009-01-27 | — | — | US | disclosed |
| US-20060241147-A1 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system | ORION CORPORATION (FI) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241147-A1 | Pyridine derivatives useful for inhibiting sodium/calcium exchange system | SLC8B1, CACNA1A, MCU | SLC8A1 5/4885HRH3 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.