Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418100 | 0.93 | CYP1A2 (0.38) | CYP1A2TSHRITGB1ITGA4KMT2A | |
| Trifluoroacetic Acid SCHEMBL4363440 | 0.91 | CTRB1 (0.35) | CTRB1DPP8DPP7CYP1A2TSHR | |
| Trifluoroacetic Acid SCHEMBL4355575 | 0.89 | EPOR (0.36) | CTRB1DPP8DPP7 | |
| Trifluoroacetic Acid SCHEMBL4359902 | 0.89 | EPOR (0.38) | CTRB1 | |
| SCHEMBL25183025 | 0.85 | CTRB1 (0.36) | CTRB1CYP1A2TSHRKMT2AGPR3 | |
| SCHEMBL30510366 | 0.82 | CTRB1 (0.40) | CTRB1CYP1A2TSHRITGB1ITGA4 | |
| SCHEMBL5407004 | 0.82 | CTRB1 (0.40) | CTRB1CYP1A2TSHRITGB1ITGA4 | |
| SCHEMBL4600752 | 0.82 | CTRB1 (0.40) | CTRB1CYP1A2TSHRITGB1ITGA4 | |
| SCHEMBL4600067 | 0.82 | CTRB1 (0.40) | CTRB1CYP1A2TSHRITGB1ITGA4 | |
| SCHEMBL1405873 | 0.82 | CYP1A2 (0.38) | CYP1A2TSHRITGB1ITGA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923397-B1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-1923397-A1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-05-21 | — | — | EP | disclosed |