Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GALR1 | P47211 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | EPOR | P19235 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4359902 | 0.94 | EPOR (0.38) | CTRB1CA12CA1CA2CA9 | |
| Trifluoroacetic Acid SCHEMBL4355575 | 0.94 | EPOR (0.36) | CTRB1DPP7DPP8CA12CA1 | |
| Trifluoroacetic Acid SCHEMBL4363452 | 0.91 | CTRB1 (0.36) | CTRB1DPP7DPP8CYP1A2TSHR | |
| SCHEMBL5548812 | 0.86 | EPOR (0.42) | DPP7CYP1A2TSHRANPEPEPOR | |
| SCHEMBL4738904 | 0.86 | EPOR (0.42) | DPP7CYP1A2TSHRANPEPEPOR | |
| SCHEMBL418100 | 0.84 | CYP1A2 (0.38) | CYP1A2TSHR | |
| SCHEMBL25183025 | 0.83 | CTRB1 (0.36) | CTRB1CYP1A2TSHR | |
| SCHEMBL8893033 | 0.83 | CYP1A2 (0.37) | CYP1A2TSHREPOR | |
| SCHEMBL8892535 | 0.83 | CYP1A2 (0.37) | CYP1A2TSHREPOR | |
| SCHEMBL25177898 | 0.83 | CYP1A2 (0.37) | CTRB1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923397-B1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-1923397-A1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-05-21 | — | — | EP | disclosed |