Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 18/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.52 |
| ▸ | LMNA | P02545 | 8/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363579 | 1.00 | MAPT (0.52) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2076697 | 0.86 | MAPT (0.64) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2079878 | 0.86 | MAPT (0.49) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL7821117 | 0.84 | MAPT (0.69) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL7821114 | 0.84 | MAPT (0.69) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3436159 | 0.79 | MAPT (0.61) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2080950 | 0.79 | L3MBTL1 (0.63) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL2080668 | 0.79 | MAPT (0.53) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3436164 | 0.79 | LMNA (0.54) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL3435561 | 0.79 | MAPT (0.54) | MAPTALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2009-11-19 | — | — | US | disclosed |
| EP-2009005-A1 | AZOLECARBOXAMIDE DERIVATIVE | Astellas Pharma Inc. (JP) | 2008-12-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286766-A1 | AZOLECARBOXAMIDE DERIVATIVE | GPR17, NTRK1, TRPV1 | MAPT 1330/4885ALDH1A1 975/4885LMNA 4712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.